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CIDEA 抗体 (C-Term)

This anti-CIDEA antibody (ABIN499625) is a Rabbit Polyclonal antibody detecting CIDEA in WB, IHC (p), EIA. Suitable for Human.
产品编号 ABIN499625
发货至: 中国

Quick Overview for CIDEA 抗体 (C-Term) (ABIN499625)

抗原

See all CIDEA 抗体
CIDEA (Cell Death-Inducing DFFA-Like Effector A (CIDEA))

适用

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宿主

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克隆类型

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多克隆

标记

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This CIDEA antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

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    C-Term

    特异性

    CIDE-A antibody was raised against a peptide corresponding to amino acids 200 to 217 of human CIDE-A. It has no cross activity to CIDE-B.

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    Human CIDE-A (C-Terminus) Peptide

    亚型

    IgG
  • 应用备注

    ELISA. Western Blot: CIDE-A antibody can be used for detection of CIDE-A at 1/1000 to 1/2000dilution. An approximately 23 kDa band can be detected. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C.
  • 抗原

    CIDEA (Cell Death-Inducing DFFA-Like Effector A (CIDEA))

    别名

    CIDE-A

    背景

    Apoptosis is related to many diseases and induced by a family of cell death receptors. Cell death signals are transduced by DD-, DED-, or CARD-containing molecules and members of the caspase family of proteases. These death signals finally cause the degradation of chromosomal DNA by activated DNase DFF40/CAD, which is chaperoned and inhibited by DFF45/ICAD (1-4). DFF45 related proteins CIDE-A and CIDE-B (for cell death-inducing DFF-like effector A and B) were recently identified (5). CIDE contains a new type of domain termed CIDE-N, which has high homology with the regulatory domains of DFF45/ICAD and DFF40/CAD (5,6). Expression of CIDE-A induces DNA fragmentation and activates apoptosis, which is inhibited by DFF45. CIDE-A is expressed in many tissues.Synonyms: CIDE A, CIDEA, Cell death activator CIDE-A, Cell death-inducing DFFA-like effector A

    基因ID

    1149

    UniProt

    O60543
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