BIRC2 抗体 (C-Term)
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Quick Overview for BIRC2 抗体 (C-Term) (ABIN499623)
抗原
See all BIRC2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- C-IAP antibody was raised against a synthetic peptide corresponding to 14 amino acids at the C-terminus of human c-IAP1 c-IAP antibody detects both c-IAP1 and c-IAP2.
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- Human cIAP (C-Terminus) Peptide
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亚型
- IgG
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应用备注
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ELISA. Western Blot: cIAP antibody can be used for the detection of c-IAP at 1 to 2 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- BIRC2 (Baculoviral IAP Repeat Containing 2 (BIRC2))
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别名
- IAP2 / BIRC2
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背景
- Apoptosis, or programmed cell death, is related to many diseases, such as cancer. Apoptosis is triggered by a variety of stimuli including members in the TNF family and can be prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family that binds to and inhibits cell death proteases (1 for review). The two isoforms of c-IAP (c-IAP1 and c-IAP2) are structurally related to XIAP, containing 3 baculoviral IAP repeat (BIR) motifs that are essential and sufficient for the binding and inhibition of caspasesSynonyms: API1, Baculoviral IAP repeat-containing protein 2, C-IAP1, HIAP-2, HIAP2, IAP homolog B, Inhibitor of apoptosis protein 2, MIHB, RING finger protein 48, RNF48, TNFR2-TRAF-signaling complex protein 2, cIAP1
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基因ID
- 329
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NCBI登录号
- NP_001157
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UniProt
- Q13490
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途径
- Apoptosis, Caspase Cascade in Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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