CDIP1 抗体 (Center)
Quick Overview for CDIP1 抗体 (Center) (ABIN499605)
抗原
See all CDIP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Center
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特异性
- This antibody reacts to CDIP.
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- CDIP antibody was raised against a 16 amino acid peptide near the center of human CDIP.
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亚型
- IgG
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anti-LITAF-Like Protein (CDIP1) (AA 1-208) antibody
CDIP1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-LITAF-Like Protein (CDIP1) (AA 100-200) antibodyCDIP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-LITAF-Like Protein (CDIP1) (Center) antibodyCDIP1 适用: 人, 小鼠 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-LITAF-Like Protein (CDIP1) antibodyCDIP1 适用: 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western Blot: CDIP antibody can be used for detection of CDIP at 1 - 2 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- CDIP1 (LITAF-Like Protein (CDIP1))
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别名
- LITAF-Like Protein
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背景
- The p53 tumor-suppressor gene integrates numerous signals that control cell life and death, loss of its functions contributes to the development of most cancers. CDIP is a novel pro-apoptotic target gene whose inhibition abrogates p53-mediated apoptotic responses. Overexpression of CDIP induced apoptosis in transfected cells while siRNA suppression of caspase-8 mRNA blocked this CDIP-induced apoptosis, indicating that the CDIP-dependent apoptosis pathway proceeds through extrinsic cell death pathway. CDIP may thus represent a novel target for drug design to maximize p53 response and sensitize tumor cells to cancer therapy. Multiple isoforms of CDIP are known to exist.Synonyms: C16orf5, CDIP, Cell death-inducing protein, Transmembrane protein I1
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基因ID
- 29965
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NCBI登录号
- NP_037531
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UniProt
- Q9H305
抗原
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