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CDIP1 抗体 (Center)

This anti-CDIP1 antibody is a 兔 多克隆 antibody detecting CDIP1 in WB 和 EIA. Suitable for 人 和 小鼠.
产品编号 ABIN499605
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CDIP1 抗体 (Center) (ABIN499605)

抗原

See all CDIP1 抗体
CDIP1 (LITAF-Like Protein (CDIP1))

适用

人, 小鼠

宿主

  • 3
  • 2

克隆类型

  • 5
多克隆

标记

  • 5
This CDIP1 antibody is un-conjugated

应用范围

  • 5
  • 3
  • 3
  • 2
  • 1
Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 2
    • 1
    • 1
    • 1
    Center

    特异性

    This antibody reacts to CDIP.

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    CDIP antibody was raised against a 16 amino acid peptide near the center of human CDIP.

    亚型

    IgG
  • 应用备注

    ELISA. Western Blot: CDIP antibody can be used for detection of CDIP at 1 - 2 μg/mL. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C.
  • 抗原

    CDIP1 (LITAF-Like Protein (CDIP1))

    别名

    LITAF-Like Protein

    背景

    The p53 tumor-suppressor gene integrates numerous signals that control cell life and death, loss of its functions contributes to the development of most cancers. CDIP is a novel pro-apoptotic target gene whose inhibition abrogates p53-mediated apoptotic responses. Overexpression of CDIP induced apoptosis in transfected cells while siRNA suppression of caspase-8 mRNA blocked this CDIP-induced apoptosis, indicating that the CDIP-dependent apoptosis pathway proceeds through extrinsic cell death pathway. CDIP may thus represent a novel target for drug design to maximize p53 response and sensitize tumor cells to cancer therapy. Multiple isoforms of CDIP are known to exist.Synonyms: C16orf5, CDIP, Cell death-inducing protein, Transmembrane protein I1

    基因ID

    29965

    NCBI登录号

    NP_037531

    UniProt

    Q9H305
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