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Caspase 6 抗体 (Intermediate Domain)

This anti-Caspase 6 antibody is a 兔 多克隆 antibody detecting Caspase 6 in WB, IF 和 EIA. Suitable for 人.
产品编号 ABIN499569
发货至: 中国

Quick Overview for Caspase 6 抗体 (Intermediate Domain) (ABIN499569)

抗原

See all Caspase 6 (CASP6) 抗体
Caspase 6 (CASP6) (Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6))

适用

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宿主

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克隆类型

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多克隆

标记

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This Caspase 6 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
  • 抗原表位

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    Intermediate Domain

    特异性

    Caspase-6 antibody was raised against a 15 amino acid peptide from near the center of human Caspase-6.

    纯化方法

    Immunoaffinity

    免疫原

    Human Casp-6 / Mch2 (Intermediate Domain) Peptide

    亚型

    IgG
  • 应用备注

    ELISA. Western Blot: Casp-6 antibody can be used for the detection of Caspase-6 at 1 μg/mL. MCF7cell lysate can be used as positive control. Depending on cell lines or tissues used, eitherfull-length or other cleavage products may be observed. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C.
  • 抗原

    Caspase 6 (CASP6) (Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6))

    别名

    Caspase-6

    背景

    Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens (reviewed in 1 and 2). The apoptotic subfamily can be further divided into initiator caspases, which are activated in response to death signals, and executioner caspases, which are activated by the initiator caspases and are responsible for cleavage of cellular substrates that ultimately lead to cell death (reviewed in 3). Caspase-6 is an executioner caspase that was identified based on its homology with human caspases 2 and 3 as well as the C. elegans cell death protein CED-3 (4). It possesses two isoforms, of which only the longer form possesses protease activity (4). Caspase-6 is highly expressed in adult brain and may play a role in several neuronal pathologies (5).Synonyms: Apoptotic protease Mch-2, CASP-6, CASP6, MCH-2, MCH2

    基因ID

    839

    NCBI登录号

    NP_001217

    UniProt

    P55212

    途径

    Apoptosis, Caspase Cascade in Apoptosis
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