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CASP5 抗体 (Intermediate Domain)

CASP5 适用: 人 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN499567
发货至: 中国
  • 抗原 See all CASP5 抗体
    CASP5 (Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5))
    抗原表位
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Intermediate Domain
    适用
    • 44
    • 8
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 41
    • 3
    克隆类型
    • 33
    • 11
    多克隆
    标记
    • 27
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This CASP5 antibody is un-conjugated
    应用范围
    • 26
    • 15
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    特异性
    Caspase-5 antibody was raised against a 14 amino acid peptide from the center of human Caspase-5.
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    Human Casp-5 / (ICH-3 / ICE rel III (Intermediate Domain) Peptide
    亚型
    IgG
    Top Product
    Discover our top product CASP5 Primary Antibody
  • 应用备注
    ELISA. Western Blot: Casp-5 antibody can be used for the detection of caspase-5 at 0.5 - 1 μg/mLDepending on cell lines or tissues used, other cleavage products may be observed. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    CASP5 (Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5))
    别名
    Caspase-5 (CASP5 产品)
    别名
    ICE(rel)III antibody, ICEREL-III antibody, ICH-3 antibody, CASP5 antibody, caspase 5 antibody, caspase-5 antibody, CASP5 antibody, LOC100437308 antibody
    背景
    Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens (reviewed in 1). Members of this subfamily include caspase-1, -4, -5, and -12. Activation of these caspases results in the cleavage and activation of proinflammatory cytokines such as IL-1beta and IL-18 (2,3). Caspase-5 can interact with caspase-1, both are constituents of the NALP1 inflammasome, a complex that can trigger the cleavage of pro-IL-1beta (4). Expression of caspase-5 can be regulated by lipopolysaccharide (LPS) and IFN-gamma (5).Synonyms: CASP-5, CASP5, ICE(rel)-III, ICH-3 protease, ICH3, TY protease
    基因ID
    838
    UniProt
    P51878
    途径
    Inflammasome
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