CASP14 抗体 (C-Term)
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Quick Overview for CASP14 抗体 (C-Term) (ABIN499557)
抗原
See all CASP14 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody reacts to Caspase-14.
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- Caspase-14 antibody was raised against a 16 amino acid peptide from near the carboxy- terminus of human caspase-14.
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亚型
- IgG
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应用备注
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ELISA. Western Blot: Caspase-14 antibody can be used for the detection of caspase-14 at 1 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- CASP14 (Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14))
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别名
- Caspase-14
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背景
- Caspases are a family of cysteine proteases that can be divided into apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. Members of this subfamily include caspase-1, -4, -5, and -12 and can activate proinflammatory cytokines such as IL-1b and IL-18. Caspase-14 is highly expressed in embryonic but not adult tissues. It is processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may be involved in the keratinocyte terminal differentiation, which is important for the formation of the skin barrier.Synonyms: CASP-14, CASP14
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基因ID
- 12365
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NCBI登录号
- NP_033939
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UniProt
- O89094
抗原
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