Calpain 6 抗体 (C-Term)
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Quick Overview for Calpain 6 抗体 (C-Term) (ABIN499521)
抗原
See all Calpain 6 (CAPN6) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody reacts to CAPN6.
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- CAPN6 antibody was raised against a 18 amino acid peptide from near the carboxy terminus of human CAPN6.
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亚型
- IgG
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anti-Calpain 6 (CAPN6) (AA 195-494) antibody
CAPN6 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Calpain 6 (CAPN6) (Internal Region) antibodyCAPN6 适用: 人, 小鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Calpain 6 (CAPN6) antibodyCAPN6 适用: 人, 小鼠 WB, FACS 宿主: 小鼠 Monoclonal 5C5 unconjugated
anti-Calpain 6 (CAPN6) (AA 390-419) antibodyCAPN6 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB19561 unconjugated
anti-Calpain 6 (CAPN6) (AA 289-319), (Middle Region) antibodyCAPN6 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western Blot: CAPN6 antibody can be used for the detection of StrepII at 0.5 - 1 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- Calpain 6 (CAPN6)
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别名
- Calpain-6
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背景
- Calpains make up a ubiquitously expressed, well-conserved family of calcium-dependent cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. This large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes as their activation can be triggered by calcium influx and oxidative stress. Calpain 6 (CAPN6) is most similar to Calpain 5, the C-terminal region of CAPN6 lacks homology to the calmodulin-like domain of other vertebrate calpains. CAPN6 is thought to be involved in the regulation of microtubule dynamics and cytoskeletal organization. CAPN6 has also been recently identified as an HIV dependency factor (HDF), suggesting that CAPN6 may be an important drug target in HIV treatment.Synonyms: CALPM, CANPX, CAPN6, Calpain-like protease X-linked, Calpamodulin
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基因ID
- 827
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NCBI登录号
- NP_055104
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UniProt
- Q9Y6Q1
抗原
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