PRDM1 抗体 (N-Term)
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Quick Overview for PRDM1 抗体 (N-Term) (ABIN499477)
抗原
See all PRDM1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody reacts to Blimp-1.
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- Blimp-1 antibody was raised against a 17 amino acid peptide from near the amino terminus of human Blimp-1.
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亚型
- IgG
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anti-PR Domain Containing 1, with ZNF Domain (PRDM1) (AA 1-109) antibody
PRDM1 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 2B10 unconjugated
anti-PR Domain Containing 1, with ZNF Domain (PRDM1) (Internal Region) antibodyVerified PRDM1 适用: 人 WB, ELISA, IHC, FACS, IF 宿主: 山羊 Polyclonal unconjugated
anti-PR Domain Containing 1, with ZNF Domain (PRDM1) (AA 690-825) antibodyPRDM1 适用: 人 ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 2F1B6 unconjugated
anti-PR Domain Containing 1, with ZNF Domain (PRDM1) (AA 1-109) antibodyPRDM1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2F8 unconjugated
anti-PR Domain Containing 1, with ZNF Domain (PRDM1) (AA 422-493) antibodyPRDM1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1G9 unconjugated
anti-PR Domain Containing 1, with ZNF Domain (PRDM1) (AA 690-825) antibodyPRDM1 适用: 人 ELISA, ICC 宿主: 小鼠 Monoclonal 7C11H1 unconjugated
anti-PR Domain Containing 1, with ZNF Domain (PRDM1) (C-Term) antibodyVerified PRDM1 适用: 人 ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-PR Domain Containing 1, with ZNF Domain (PRDM1) (Middle Region) antibodyPRDM1 适用: 人, 小鼠, 大鼠, 犬, Pig, Cow, 马, 兔, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-PR Domain Containing 1, with ZNF Domain (PRDM1) (AA 199-409) antibodyPRDM1 适用: 人, 小鼠, Pig WB, ELISA, IHC, IP, ICC, FACS, IF 宿主: 小鼠 Monoclonal 3H2-E8 unconjugated
anti-PR Domain Containing 1, with ZNF Domain (PRDM1) (AA 29-149) antibodyPRDM1 适用: 人 WB, FACS 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western Blot: Blimp-1 antibody can be used for detection of Blimp-1 by Western blot at 0.5- 1 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- PRDM1 (PR Domain Containing 1, with ZNF Domain (PRDM1))
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别名
- PRDM1 / BLIMP1
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背景
- Blimp-1 was initially identified as a zinc finger-containing protein that drives the maturation of B lymphocytes into immunoglobulin-secreting cells (1). Together with X-box-binding protein 1 (XBP1), Blimp-1 is induced upon terminal differentiation of plasma cells (2,3). The transcriptional repressor activity of Blimp-1 has also been found to regulate T cell homeostasis and function, possibly by suppressing the expression of the cytokines IL-2 and interferon-gamma during T cell development (4). More recent experiments have suggested that Blimp-1 also plays a major role in the formation of primordial germ cells (PGC) in developing mammalian embryos. In these experiments, Blimp-1-deficient mutant mouse embryos form a cluster of PGC-like cells which fail to show the expected migration, proliferation, and repression of homeobox genes that normally accompany specification of primordial germ cells (5). Blimp-1 exists as at least two different isoforms.Synonyms: BLIMP-1, Beta-interferon gene positive regulatory domain I-binding factor, PR domain zinc finger protein 1, PR domain-containing protein 1, PRDI-BF1, PRDI-binding factor 1, Positive regulatory domain I-binding factor 1
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基因ID
- 639
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NCBI登录号
- NP_001189
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UniProt
- O75626
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途径
- Regulation of Muscle Cell Differentiation
抗原
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