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BIM 抗体 (Intermediate Domain 2)

This anti-BIM antibody is a 兔 多克隆 antibody detecting BIM in WB, IF 和 EIA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN499469
发货至: 中国

Quick Overview for BIM 抗体 (Intermediate Domain 2) (ABIN499469)

抗原

See all BIM (BCL2L11) 抗体
BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))

适用

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人, 小鼠, 大鼠

宿主

  • 108
  • 9
  • 3
  • 1

克隆类型

  • 93
  • 28
多克隆

标记

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This BIM antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
  • 抗原表位

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    Intermediate Domain 2

    特异性

    Bim antibody was raised against a peptide corresponding to amino acids near the center of Bim.

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    Human Bim (Intermediate Domain 2) Peptide

    亚型

    IgG
  • 应用备注

    ELISA. Western Blot: Bim antibody can be used for detection of Bim at 2.5 μg/mL. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C.
  • 抗原

    BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))

    背景

    Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, and Hrk, form a growing subclass of the Bcl-2 family. A novel BH3 domain containing protein was recently identified and designated Bim or BOD in human, mouse and rat (1,2). Bim/BOD interacts with diverse members in the pro-survival Bcl-2 sub-family including Bcl-2, Bcl-xL and Bcl-w. Bim/BOD induces apoptosis. The messenger RNA of Bim is ubiquitously expressed in multiple tissues and cell lines (1,2).Synonyms: BCL2L11, BIM, Bcl2-L-11, Bcl2-interacting mediator of cell death, BimEL, BimL, BimS

    基因ID

    10018

    NCBI登录号

    NP_619527

    UniProt

    O43521

    途径

    PI3K-Akt Signaling, Neurotrophin Signaling Pathway, Tube Formation, Positive Regulation of Endopeptidase Activity
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