BIM 抗体 (Intermediate Domain 2)
Our Local Distributor
北京 101111
Quick Overview for BIM 抗体 (Intermediate Domain 2) (ABIN499469)
抗原
See all BIM (BCL2L11) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Intermediate Domain 2
-
特异性
- Bim antibody was raised against a peptide corresponding to amino acids near the center of Bim.
-
纯化方法
- Affinity chromatography purified via peptide column
-
免疫原
- Human Bim (Intermediate Domain 2) Peptide
-
亚型
- IgG
-
-
-
-
应用备注
-
ELISA. Western Blot: Bim antibody can be used for detection of Bim at 2.5 μg/mL. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
缓冲液
- PBS containing 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
储存方法
- Store the antibody undiluted at 2-8 °C.
-
-
- BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))
-
背景
- Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, and Hrk, form a growing subclass of the Bcl-2 family. A novel BH3 domain containing protein was recently identified and designated Bim or BOD in human, mouse and rat (1,2). Bim/BOD interacts with diverse members in the pro-survival Bcl-2 sub-family including Bcl-2, Bcl-xL and Bcl-w. Bim/BOD induces apoptosis. The messenger RNA of Bim is ubiquitously expressed in multiple tissues and cell lines (1,2).Synonyms: BCL2L11, BIM, Bcl2-L-11, Bcl2-interacting mediator of cell death, BimEL, BimL, BimS
-
基因ID
- 10018
-
NCBI登录号
- NP_619527
-
UniProt
- O43521
-
途径
- PI3K-Akt Signaling, Neurotrophin Signaling Pathway, Tube Formation, Positive Regulation of Endopeptidase Activity
抗原
-