SH3GLB1 抗体 (C-Term)
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北京 101111
Quick Overview for SH3GLB1 抗体 (C-Term) (ABIN499465)
抗原
See all SH3GLB1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This anitbody reacts to BIF.
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- BIF antibody was raised against a 15 amino acid peptide from near the carboxy terminus of human BIF.
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亚型
- IgG
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anti-SH3-Domain GRB2-Like Endophilin B1 (SH3GLB1) (C-Term) antibody
Verified SH3GLB1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, FACS 宿主: 山羊 Polyclonal unconjugated
anti-SH3-Domain GRB2-Like Endophilin B1 (SH3GLB1) (AA 1-365) antibodySH3GLB1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1B3-A5 unconjugated
anti-SH3-Domain GRB2-Like Endophilin B1 (SH3GLB1) (AA 1-365) antibodySH3GLB1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-SH3-Domain GRB2-Like Endophilin B1 (SH3GLB1) (C-Term) antibodySH3GLB1 适用: 人, 小鼠 WB, IHC, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-SH3-Domain GRB2-Like Endophilin B1 (SH3GLB1) (AA 1-366) antibodySH3GLB1 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 1B3-A5 unconjugated
anti-SH3-Domain GRB2-Like Endophilin B1 (SH3GLB1) (AA 120-365) antibodySH3GLB1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-SH3-Domain GRB2-Like Endophilin B1 (SH3GLB1) (AA 59-86) antibodySH3GLB1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB15350 unconjugated
anti-SH3-Domain GRB2-Like Endophilin B1 (SH3GLB1) (AA 1-365) antibodySH3GLB1 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-SH3-Domain GRB2-Like Endophilin B1 (SH3GLB1) (AA 58-107) antibodySH3GLB1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 马, 猴, 非洲爪蟾, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-SH3-Domain GRB2-Like Endophilin B1 (SH3GLB1) (N-Term) antibodySH3GLB1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western BLot: BIF antibody can be used for the detection of BIF at 1 - 2 μg/mL. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- SH3GLB1 (SH3-Domain GRB2-Like Endophilin B1 (SH3GLB1))
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别名
- Endophilin-B1
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背景
- Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells and is caused by the activation of proteolytic enzymes termed caspases. Proteins that comprise the Bcl-2 family such as Bax appear to control the activation of these enzymes. Bax activity was found to be regulated by its association with Bax-interacting factor 1 (BIF), a member of the endophilin B family that is associated with intracellular membranes.. Following this interaction, Bax undergoes a conformational change and translocates to mitochondrial membranes. The Bax/BIF interaction appears to be enhanced by apoptotic stimuli, suggesting that BIF acts as the trigger to activate Bax, and as suppression of BIF promoted HeLa cell colony formation in soft agar, it may have a role in the suppression of cancer progression. At least two isoforms of BIF are known to exist.Synonyms: BIF1, Bax-interacting factor 1, Bif-1, KIAA0491, SH3 domain-containing GRB2-like protein B1, SH3GLB1
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基因ID
- 51100
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UniProt
- Q9Y371
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途径
- Autophagy
抗原
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