BACE2 抗体 (N-Term)
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Quick Overview for BACE2 抗体 (N-Term) (ABIN499395)
抗原
See all BACE2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- BACE2 antibody was raised against a synthetic peptide corresponding to amino acids 44 to 59 of human BACE2.
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- Human BACE2 (N-Terminus) Peptide
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亚型
- IgG
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anti-beta-Site APP-Cleaving Enzyme 2 (BACE2) (AA 230-396) antibody
BACE2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-beta-Site APP-Cleaving Enzyme 2 (BACE2) (AA 242-502) antibodyBACE2 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-beta-Site APP-Cleaving Enzyme 2 (BACE2) (AA 156-407) antibodyBACE2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-beta-Site APP-Cleaving Enzyme 2 (BACE2) (AA 84-157) antibodyBACE2 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-beta-Site APP-Cleaving Enzyme 2 (BACE2) (AA 44-59) antibodyBACE2 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-beta-Site APP-Cleaving Enzyme 2 (BACE2) (C-Term) antibodyBACE2 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-beta-Site APP-Cleaving Enzyme 2 (BACE2) antibodyBACE2 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal 1-9 unconjugated Recombinant Antibody
anti-beta-Site APP-Cleaving Enzyme 2 (BACE2) (AA 336-365) antibodyBACE2 适用: 人 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-beta-Site APP-Cleaving Enzyme 2 (BACE2) (AA 101-200) antibodyBACE2 适用: 大鼠 ELISA, ICC, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-beta-Site APP-Cleaving Enzyme 2 (BACE2) (AA 306-395) antibodyBACE2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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ELISA. Western Blot: BACE2 can be used for detection of BACE2 at 0.5 to 1 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- BACE2 (beta-Site APP-Cleaving Enzyme 2 (BACE2))
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别名
- BACE2
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背景
- Accumulation of the amyloid-beta (alphabeta) plaque in the cerebral cortex is a critical event in the pathogenesis of Alzheimer's disease. alphabeta peptide is generated by proteolytic cleavage of the beta-amyloid protein precursor (APP) at beta- and gamma-sites by proteases. The long-sought beta-secretase was recently identified by several groups independently and designated beta-site APP cleaving enzyme (BACE) and aspartyl protease 2 (Asp2) (1-4). A BACE homolog was recently cloned and designated BACE2, Asp1, DRAP (for Down region aspartic protease), and memapsin 1 (4-9). BACE2 also cleaves APP at beta-site and at a different site within alphabeta (8). BACE2 locates on chromosome 21q22.3, the so-called 'Down critical region', suggesting that BACE2 and alphabeta may also contribute to the pathogenesis of Down syndrome (6,7)Synonyms: AEPLC, ALP56, ASP1, ASP21, Aspartic-like protease 56 kDa, Aspartyl protease 1, Beta-secretase 2, Beta-site APP-cleaving enzyme 2, Down region aspartic protease, Memapsin-1, Membrane-associated aspartic protease 1
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基因ID
- 25825
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UniProt
- Q9Y5Z0
抗原
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