ATOH8 抗体 (C-Term)
Quick Overview for ATOH8 抗体 (C-Term) (ABIN499361)
抗原
See all ATOH8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody reacts to ATOH8.
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- ATOH8 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human ATOH8.
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亚型
- IgG
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anti-Atonal Homolog 8 (ATOH8) (C-Term) antibody
ATOH8 适用: 人 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Atonal Homolog 8 (ATOH8) (N-Term) antibodyATOH8 适用: 人, Cow, 犬, 马, 兔, Pig, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Atonal Homolog 8 (ATOH8) (C-Term) antibodyATOH8 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠, Pig, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Atonal Homolog 8 (ATOH8) (AA 10-39), (N-Term) antibodyATOH8 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB33477 unconjugated
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应用备注
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ELISA. Western Blot: ATOH8 antibody can be used for detection of ATOH8 at 1 - 2 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- ATOH8 (Atonal Homolog 8 (ATOH8))
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别名
- ATOH8
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背景
- Basic helix-loop-helix (bHLH) transcription factors play important roles in differentiation processes during embryonic development of vertebrates. ATOH8 (MATH6) is a tissue-restricted member of the atonal superfamily of bHLH transcription factors that exhibits 43-57 % identity in the bHLH domain with other mammalian atonal paralogs including the NeuroD and Neurogenin factors. In the mouse, ATOH8 has been implicated in the specification and differentiation of neuronal cell lineages in the brain and may also participate in kidney development. Recent studies show that ATOH8 is a novel component of the pancreatic transcriptional network during embryonic development and suggest a potential role as a modulator of the differentiation program initiated by the pro-endocrine factor Neurog3. It is indispensable for early embryonic development, suggesting a more widespread function for this factor in tissue-specific differentiation processes that are dependent on class II bHLH genes.Synonyms: Helix-loop-helix protein hATH-6, Protein atonal homolog 8, hATH-6, hATH6
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基因ID
- 84913
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NCBI登录号
- NP_116216
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UniProt
- Q96SQ7
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途径
- Regulation of Muscle Cell Differentiation
抗原
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