NOL3 抗体 (C-Term)
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Quick Overview for NOL3 抗体 (C-Term) (ABIN499327)
抗原
See all NOL3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- ARC antibody was raised against a peptide corresponding to amino acids 191 to 208 of human origin.
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- Human ARC (C-Terminus) Peptide
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亚型
- IgG
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应用备注
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ELISA. Western Blot: ARC antibody can be used for detection of ARC at 1/1000 dilution. Anapproximately 25 kDa band can be detected. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- NOL3 (Nucleolar Protein 3 (Apoptosis Repressor with CARD Domain) (NOL3))
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别名
- NOL3 / ARC
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背景
- Apoptosis is regulated by death domain (DD) and/or caspase recruitment domain (CARD) containing molecules and a caspase family of proteases. CARD domain containing cell death regulators include RAIDD, Apaf-1, caspase-9, and caspase-2. A novel CARD domain containing protein was recently identified and designated ARC for apoptosis repressor with CARD (1). ARC interacts with caspase-2 and -8 and inhibits enzymatic activity of caspase-8. ARC suppresses apoptosis induced by cell death adapters FADD and TRADD and by cell death receptors Fas, TNFR-1 and DR3. The messenger RNA of ARC is primarily expressed in skeletal muscle and cardiac tissue (1).Synonyms: Apoptosis repressor with CARD, Muscle-enriched cytoplasmic protein, Myp, NOP, Nop30, Nucleolar protein 3, Nucleolar protein of 30 kDa
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基因ID
- 8996
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NCBI登录号
- NP_003937
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UniProt
- O60936
抗原
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