APP 抗体 (C-Term)
Quick Overview for APP 抗体 (C-Term) (ABIN499317)
抗原
See all APP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- APP antibody was raised against a peptide corresponding to amino acids 737 to 751 of human amyloid A4 protein precursor (APP) or 85 to 99 of the C99 fragment generated by b-secretase cleavage. The peptide sequences are identical to those of monkey, mouse, rat, chicken, and a variety of other species.
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- Human APP (C-Terminus) Peptide
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亚型
- IgG
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anti-Amyloid beta (A4) Precursor Protein (APP) (C-Term) antibody
APP 适用: 人 WB, IF, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Amyloid beta (A4) Precursor Protein (APP) antibodyAPP 适用: 人, 小鼠 WB, ELISA, IHC, IF, FM 宿主: 兔 Polyclonal unconjugated
anti-Amyloid beta (A4) Precursor Protein (APP) (AA 666-670) antibodyAPP 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Amyloid beta (A4) Precursor Protein (APP) (AA 18-270) antibodyAPP 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Amyloid beta (A4) Precursor Protein (APP) (C-Term) antibodyAPP 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Amyloid beta (A4) Precursor Protein (APP) antibodyKO Validated APP 适用: 人 WB, IHC, IF, IP 宿主: 兔 Monoclonal unconjugated
anti-Amyloid beta (A4) Precursor Protein (APP) (AA 381-480) antibodyAPP 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), ICC, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Amyloid beta (A4) Precursor Protein (APP) (pThr668) antibodyAPP 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Amyloid beta (A4) Precursor Protein (APP) antibodyAPP 适用: 人 WB, ELISA, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Amyloid beta (A4) Precursor Protein (APP) (C-Term) antibodyAPP 适用: 人, 小鼠, 大鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western Blot: APP antibody can be used for detection of APP and the C99 fragment at 1 - 2 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- APP (Amyloid beta (A4) Precursor Protein (APP))
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别名
- Amyloid beta A4 Protein / APP
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背景
- Accumulation of the amyloid-beta peptide (alpha beta) in the cerebral cortex is a critical event in the pathogenesis of Alzheimer's disease. The b-amyloid protein precursor (APP) is cleaved by beta-secretase, producing a soluble derivative of the protein and a membrane anchored 99-amino acid carboxy-terminal fragment (C99). The C99 fragment serves as substrate for g-secretase to generate the 4 kDa amyloid-beta peptide (alpha beta), which is deposited in the brains of all suffers of Alzheimer's disease.Synonyms: ABPP, APPI, Alzheimer disease amyloid protein, Amyloid Precursor Protein, CVAP, Cerebral vascular amyloid peptide, PreA4, Protease nexin-II
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基因ID
- 351
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UniProt
- P05067
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途径
- Caspase Cascade in Apoptosis, EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, Feeding Behaviour
抗原
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