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ANAPC5 抗体 (Center)

The 兔 多克隆 anti-ANAPC5 antibody (ABIN499299) specifically detects ANAPC5 in WB 和 EIA. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN499299
发货至: 中国
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Quick Overview for ANAPC5 抗体 (Center) (ABIN499299)

抗原

See all ANAPC5 抗体
ANAPC5 (Anaphase Promoting Complex Subunit 5 (ANAPC5))

适用

  • 54
  • 14
  • 5
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 53
  • 1

克隆类型

  • 54
多克隆

标记

  • 22
  • 5
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This ANAPC5 antibody is un-conjugated

应用范围

  • 43
  • 22
  • 13
  • 13
  • 8
  • 7
  • 5
  • 4
  • 3
  • 3
  • 2
  • 1
Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 15
    • 8
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Center

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    APC5 antibody was raised against a 17 amino acid peptide near the center of human APC5.

    亚型

    IgG
  • 应用备注

    ELISA. Western Blot: APC5 antibody can be used for detection of APC5 at 1 - 2 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store the antibody (in aliquots) at -20 °C.
  • 抗原

    ANAPC5 (Anaphase Promoting Complex Subunit 5 (ANAPC5))

    别名

    APC5 / ANAPC5

    背景

    Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC5 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex. While little is known of APC5, it is thought that APC5 associates with other APC/C components APC1, APC4, and CDC23 interdependently, such that loss of any one subunit reduces binding between the remaining three.Synonyms: Anaphase-promoting complex subunit 5, Cyclosome subunit 5

    基因ID

    51433

    UniProt

    Q9UJX4

    途径

    M Phase
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