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- 抗原 See all ANAPC4 抗体
- ANAPC4 (Anaphase Promoting Complex Subunit 4 (ANAPC4))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ANAPC4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- APC4 antibody was raised against a 14 amino acid peptide near the amino terminus of human APC4.
- 亚型
- IgG
- Top Product
- Discover our top product ANAPC4 Primary Antibody
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anti-Anaphase Promoting Complex Subunit 4 (ANAPC4) (AA 1-808) antibody
ANAPC4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA. Western Blot: APC4 antibody can be used for detection of APC4 at 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- Store the antibody (in aliquots) at -20 °C.
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- 抗原
- ANAPC4 (Anaphase Promoting Complex Subunit 4 (ANAPC4))
- 别名
- APC4 / ANAPC4 (ANAPC4 产品)
- 背景
- Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC4 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex. While little is known of APC4, it is thought that APC4 associates with other APC/C components APC1, APC5, and CDC23 interdependently, such that loss of any one subunit reduces binding between the remaining three.Synonyms: Anaphase-promoting complex subunit 4, Cyclosome subunit 4
- 基因ID
- 29945
- UniProt
- Q9UJX5
- 途径
- M Phase
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