APC2 抗体 (Center)
Quick Overview for APC2 抗体 (Center) (ABIN499293)
抗原
See all APC2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Center
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- APC2 antibody was raised against an 18 amino acid peptide near the center of human APC2.
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亚型
- IgG
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anti-APC Regulator of WNT Signaling Pathway 2 (APC2) (AA 2041-2181) antibody
APC2 适用: 人 ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 3A2G2 unconjugated
anti-APC Regulator of WNT Signaling Pathway 2 (APC2) (AA 849-898) antibodyAPC2 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 猴, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-APC Regulator of WNT Signaling Pathway 2 (APC2) (AA 2011-2221) antibodyAPC2 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-APC Regulator of WNT Signaling Pathway 2 (APC2) (AA 122-152) antibodyAPC2 适用: 人 WB 宿主: 兔 Polyclonal RB53935 unconjugated
anti-APC Regulator of WNT Signaling Pathway 2 (APC2) (Middle Region) antibodyAPC2 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western Blot: APC2 antibody can be used for detection of APC2 at 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody (in aliquots) at -20 °C.
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- APC2 (APC Regulator of WNT Signaling Pathway 2 (APC2))
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别名
- APC2
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背景
- Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC2 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex. Like APC11, APC2 contains cullin and RING finger domains that are thought to be important in regulating ubiquitination activity.Synonyms: APC-like, APCL, Adenomatous polyposis coli protein 2, Adenomatous polyposis coli protein-like
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基因ID
- 10297
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UniProt
- O95996
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途径
- WNT signaling
抗原
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