ALDH5A1 抗体 (C-Term)
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Quick Overview for ALDH5A1 抗体 (C-Term) (ABIN499267)
抗原
See all ALDH5A1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody reacts to ALDH5A1.
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- Aldh5A1 antibody was raised against a 22 amino acid peptide near the carboxy terminus of the human Aldh5A1.
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亚型
- IgG
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应用备注
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ELISA. Western Blot: Aldh5A1 antibody can be used for detection of Aldh5A1 at 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- ALDH5A1 (Aldehyde Dehydrogenase 5 Family, Member A1 (ALDH5A1))
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别名
- ALDH5A1 / SSADH
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背景
- Aldh5A1 is a member of the aldehyde dehydrogenase superfamily, a group of NAD(P)(+)-dependent enzymes that catalyze the oxidation of a wide spectrum of aliphatic and aromatic aldehydes. Aldehyde dehydrogenase enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. Aldh5A1 is a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, results in a disorder of the neurotransmitter 4-aminobutyric acid (GABA). Symptoms usually include static encephalopathy, associated with developmental delays, hypotonia, ataxia, speech defects, and seizures. At least two isoforms of Aldh5A1 are known to exist.Synonyms: Aldehyde dehydrogenase family 5 member A1, NAD(+)-dependent succinic semialdehyde dehydrogenase, Succinate-semialdehyde dehydrogenase, mitochondrial
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基因ID
- 7915
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NCBI登录号
- NP_733936
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UniProt
- P51649
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途径
- Monocarboxylic Acid Catabolic Process
抗原
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