AICDA 抗体 (C-Term)
(1 reference)Quick Overview for AICDA 抗体 (C-Term) (ABIN499233)
抗原
See all AICDA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody recognizes AID (C-term).
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- A Peptide corresponding to 14 amino acids near the carboxy-terminus of Human AID
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亚型
- IgG
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anti-Activation-Induced Cytidine Deaminase (AICDA) (N-Term) antibody
AICDA 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Activation-Induced Cytidine Deaminase (AICDA) (Internal Region) antibodyAICDA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Activation-Induced Cytidine Deaminase (AICDA) (AA 1-60) antibodyAICDA 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Activation-Induced Cytidine Deaminase (AICDA) (N-Term) antibodyVerified AICDA 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Activation-Induced Cytidine Deaminase (AICDA) (AA 1-198) antibodyAICDA 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Activation-Induced Cytidine Deaminase (AICDA) (N-Term) antibodyAICDA 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Activation-Induced Cytidine Deaminase (AICDA) (AA 178-198) antibodyAICDA 适用: 人, 小鼠 WB, IF, IP 宿主: 大鼠 Monoclonal 328-8b unconjugated
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应用备注
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ELISA. Western Blot: AID antibody can be used for detection of AID at 1 - 2 μg/mL. Whole cell lysatefrom Ramos cells can be used as positive control. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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: "Defective activation of the MAPK/ERK pathway, leading to PARP1 and DNMT1 dysregulation, is a common defect in IgA nephropathy and Henoch-Schönlein purpura." in: Journal of nephrology, Vol. 31, Issue 5, pp. 731-741, (2018) (PubMed).
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: "Defective activation of the MAPK/ERK pathway, leading to PARP1 and DNMT1 dysregulation, is a common defect in IgA nephropathy and Henoch-Schönlein purpura." in: Journal of nephrology, Vol. 31, Issue 5, pp. 731-741, (2018) (PubMed).
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- AICDA (Activation-Induced Cytidine Deaminase (AICDA))
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别名
- AICDA / AID
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背景
- Activation-induced cytidine deaminase (AID) was initially discovered as a homolog of the apolipoprotein B RNA-editing cytidine deaminase 1 (APOBEC1) that showed cytidine deaminase properties in stimulated B cell lines (1). It is necessary for somatic hypermutation and class switch recombination in B cells (2), but inappropriate or dysregulated expression AID is often found in tumors and B cell neoplasms (2,3). Although it is structurally and functionally similar to the APOBEC proteins (reviewed in 4), it appears unlikely that AID deaminates dC to dU residues in HIV cDNA as does APOBEC3G (5).Synonyms: Activation-induced cytidine deaminase, Cytidine aminohydrolase
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基因ID
- 57379
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NCBI登录号
- NP_065712
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UniProt
- Q9GZX7
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途径
- Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Production of Molecular Mediator of Immune Response
抗原
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