AICDA 抗体 (AA 178-198)
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Quick Overview for AICDA 抗体 (AA 178-198) (ABIN2668532)
抗原
See all AICDA 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 178-198
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原理
- AID antibody (mAb) (Clone 328.8b)
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纯化方法
- Protein G Chromatography
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免疫原
- This AID antbody was raised against a peptide corresponding to amino acids 178-198 of human AID.
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亚型
- IgG2a
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anti-Activation-Induced Cytidine Deaminase (AICDA) (N-Term) antibody
AICDA 适用: 人 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Activation-Induced Cytidine Deaminase (AICDA) (C-Term) antibodyAICDA 适用: 人, 小鼠 WB, IHC, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Activation-Induced Cytidine Deaminase (AICDA) (Internal Region) antibodyAICDA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Activation-Induced Cytidine Deaminase (AICDA) (C-Term) antibodyAICDA 适用: 人, 小鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
anti-Activation-Induced Cytidine Deaminase (AICDA) (AA 1-198) antibodyAICDA 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Activation-Induced Cytidine Deaminase (AICDA) (N-Term) antibodyVerified AICDA 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Activation-Induced Cytidine Deaminase (AICDA) (N-Term) antibodyAICDA 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Activation-Induced Cytidine Deaminase (AICDA) (AA 1-60) antibodyAICDA 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1 - 3 μg/mL dilution
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限制
- 仅限研究用
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浓度
- 1 μg/μL
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缓冲液
- Purified IgG in 50 mM Tris-HCl ( pH 7.2), 30 % glycerol, and 0.035 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage
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储存条件
- -20 °C
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储存方法
- Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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有效期
- 24 months
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: "Alternative end-joining and classical nonhomologous end-joining pathways repair different types of double-strand breaks during class-switch recombination." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 191, Issue 11, pp. 5751-63, (2013) (PubMed).
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- AICDA (Activation-Induced Cytidine Deaminase (AICDA))
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别名
- AID
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背景
- AID (Activation-induced cytidine deaminase, AICDA) is a member of the cytidine and deoxycytidylate deaminase family. It acts act as a single-strand DNA deaminase involved in somatic hypermutation, gene conversion and class-switch recombination in developing B-cells and is necessary for efficient antibody responses. It has also been implicated in active DNA demethylation, as deamination of methylcytosine yields thymine, which is read as a mismatch and is replaced by DNA damage repair enzymes.
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分子量
- 24 kDa
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基因ID
- 57379
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NCBI登录号
- NP_065712
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途径
- Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Production of Molecular Mediator of Immune Response
抗原
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