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ACE2 抗体 (C-Term)

Name: ACE2 抗体 (C-Term)
SKU: ABIN499191
Availability: OutOfStock

ACE2 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated

Western blot analysis of ACE2 in human kidney lysate with AP30007PU-N ACE2 antibody at 0. (ACE2 抗体 (C-Term))

Immunohistochemical staining of human kidney tissue using AP30007PU-N ACE2 antibody at 2 μg/ml. (ACE2 抗体 (C-Term))

IHC (p)

2 images

产品编号 ABIN499191

发货至: 中国

Datasheet as PDF

抗原 See all ACE2 抗体

ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))
抗原表位
16

14

11

9

9

9

6

5

5

4

4

3

3

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
C-Term
适用
132

54

47

6

5

1

1

1

1

1

1
人
宿主
120

19

6
兔
Compatible Secondaries
克隆类型
108

37
多克隆
标记
78

16

10

8

5

4

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1
This ACE2 antibody is un-conjugated
应用范围
120

68

50

36

33

19

17

10

10

10

10

5

3

1

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

特异性

ACE2 antibody was raised against a synthetic peptide corresponding to amino acids near the C-terminus of human ACE2. Anti-ACE2 has no cross response to ACE1.

纯化方法

Affinity chromatography purified via peptide column

免疫原

Human ACE2 (C-Terminus) Peptide

亚型

IgG

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ACE2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

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anti-Angiotensin I Converting Enzyme 2 (ACE2) (AA 773-805) antibody
ACE2 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Angiotensin I Converting Enzyme 2 (ACE2) (AA 140-172) antibody
ACE2 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated

应用备注

ELISA. Western Blot: ACE2 antibody can be used for the detection of ACE2 at 0.5 to 2 μg/mL. A 90 kDa band can be detected. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

限制

仅限研究用
缓冲液

PBS containing 0.02 % sodium azide.

储存液

Sodium azide

注意事项

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C

储存方法

Store the antibody undiluted at 2-8 °C.
抗原

ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))

别名

ACE2 (ACE2 产品)

别名

ACE1 antibody, CD143 antibody, DCP antibody, DCP1 antibody, ICH antibody, MVCD3 antibody, ACEH antibody, 2010305L05Rik antibody, zgc:92514 antibody, angiotensin I converting enzyme antibody, angiotensin I converting enzyme 2 antibody, angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 antibody, ACE antibody, ACE2 antibody, Ace2 antibody, ace2 antibody

背景

Angiotensin-converting enzyme 2 (ACE2) plays a central role in vascular, renal, and myocardial physiology (1-2). In contrast to its homolog ACE, ACE2 expression is restricted to heart, kidney, and testis. Recently. ACE2 has also been shown to be a functional receptor of the SARS coronavirus (3). The normal function of ACE2 is to convert the inactive vasoconstrictor angiotensin I (AngI) to Ang1-9 and the active form AngII to Ang1-7, unlike ACE, which converts AngI to AngII. While the role of these vasoactive peptides is not well understood, lack of ACE2 expression in ace2-/ace2- mice leads to severely reduced cardiac contractility, indicating its importance in regulating heart function (4).Synonyms: ACE-related carboxypeptidase, Angiotensin-converting enzyme 2, Angiotensin-converting enzyme homolog

基因ID

59272

NCBI登录号

NP_068576

UniProt

Q9BYF1

途径

ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour