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ACE2 抗体 (Intermediate Domain 1)

ACE2 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN499189
发货至: 中国
  • 抗原 See all ACE2 抗体
    ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))
    抗原表位
    • 16
    • 13
    • 12
    • 8
    • 8
    • 8
    • 6
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    • 1
    • 1
    • 1
    • 1
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    Intermediate Domain 1
    适用
    • 125
    • 53
    • 47
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 113
    • 19
    • 6
    克隆类型
    • 102
    • 36
    多克隆
    标记
    • 72
    • 16
    • 10
    • 8
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ACE2 antibody is un-conjugated
    应用范围
    • 114
    • 65
    • 50
    • 36
    • 29
    • 19
    • 17
    • 10
    • 10
    • 10
    • 10
    • 5
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    ACE2 antibody was raised against a synthetic peptide corresponding to amino acids near the center of human ACE2. Anti-ACE2 has no cross response to ACE1.
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    Human ACE2 (Intermediate Domain 1) Peptide
    亚型
    IgG
    Top Product
    Discover our top product ACE2 Primary Antibody
  • 应用备注
    ELISA. Western Blot: ACE2 antibody can be used for the detection of ACE2 at 0.5 to 2 μg/mL. A 90 kDa band can be detected. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))
    别名
    ACE2 (ACE2 产品)
    别名
    ACE1 antibody, CD143 antibody, DCP antibody, DCP1 antibody, ICH antibody, MVCD3 antibody, ACEH antibody, 2010305L05Rik antibody, zgc:92514 antibody, angiotensin I converting enzyme antibody, angiotensin I converting enzyme 2 antibody, angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 antibody, ACE antibody, ACE2 antibody, Ace2 antibody, ace2 antibody
    背景
    Angiotensin-converting enzyme 2 (ACE2) plays a central role in vascular, renal, and myocardial physiology (1-2). In contrast to its homolog ACE, ACE2 expression is restricted to heart, kidney, and testis. Recently. ACE2 has also been shown to be a functional receptor of the SARS coronavirus (3). The normal function of ACE2 is to convert the inactive vasoconstrictor angiotensin I (AngI) to Ang1-9 and the active form AngII to Ang1-7, unlike ACE, which converts AngI to AngII. While the role of these vasoactive peptides is not well understood, lack of ACE2 expression in ace2-/ace2- mice leads to severely reduced cardiac contractility, indicating its importance in regulating heart function (4).Synonyms: ACE-related carboxypeptidase, Angiotensin-converting enzyme 2, Angiotensin-converting enzyme homolog
    基因ID
    59272
    NCBI登录号
    NP_068576
    UniProt
    Q9BYF1
    途径
    ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour
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