Decorin 抗体 (Internal Region)
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Quick Overview for Decorin 抗体 (Internal Region) (ABIN499170)
抗原
See all Decorin (DCN) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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序列
- C-KISRVDAASL KGLNN
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特异性
- This antibody detects Decorin (Internal). It is expected to recognize the three reported isoforms a, b and c (NP_001911.1, NP_598011.1, NP_598012.1 resp.). Reported variants NP_598010.1 and NP_001911.1 represent identical protein.
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交叉反应 (详细)
- Species reactivity (expected):Cow, pig, caviaSpecies reactivity (tested):Human
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纯化方法
- Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
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免疫原
- Peptide from the internal region of the protein sequence according to NP_001911.1, NP_598011.1, NP_598012.1
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应用备注
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Peptide ELISA: limit dilution 1: 8000. Western blot: 0.5-2 μg/mL. Approx 38 kDa band observed in Human Kidney lysates(calculated MW of 39.8 kDa according to NP_001911.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C up to one week or (in aliquots) at -20 °C for longer.
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- Decorin (DCN)
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别名
- Decorin
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背景
- Decorin is a member of the small, leucine rich proteoglycan (SLRP) family along with biglycan. Found in the interterritorial region of cartilage, decorin interacts with collagen and other matrix proteins to regulate the cartilaginous matrix. It has been shown to interact with fibronectin, thrombospondin, C1q, epidermal growth factor receptor (EGFR), and TGF beta. It is believed that decorin also plays a role in the cell cycle of chondrocytes.Synonyms: Bone proteoglycan II, DCN, PG-S2, PG40, SLRR1B
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基因ID
- 1634
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NCBI登录号
- NP_001911
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UniProt
- P07585
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途径
- Glycosaminoglycan Metabolic Process
抗原
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