MYO5A 抗体 (Internal Region)
Quick Overview for MYO5A 抗体 (Internal Region) (ABIN499147)
抗原
See all MYO5A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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序列
- C-ETKQLELDLN
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特异性
- This antibody is expected to recognize both reported isoforms (NP_000250.3 and NP_001135967.1).
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交叉反应 （详细）
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Species reactivity (expected):Rat, Bovine.
Species reactivity (tested):Human, Mouse. -
纯化方法
- Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
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免疫原
- Peptide sequence from the internal region of the protein sequence according to NP_000250.3, NP_001135967.1. Genename: MYO5A
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anti-Myosin VA (MYO5A) (AA 1087-1220) antibody
MYO5A 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Myosin VA (MYO5A) (AA 1531-1855) antibodyMYO5A 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Myosin VA (MYO5A) (Internal Region) antibodyVerified MYO5A 适用: 人, 小鼠 WB, ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-Myosin VA (MYO5A) (C-Term) antibodyMYO5A 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Myosin VA (MYO5A) (C-Term) antibodyMYO5A 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Myosin VA (MYO5A) (AA 950-1150) antibodyMYO5A 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Peptide ELISA: Limit Dilution: 1/8000. Western blot: 1-3 μg/mL. This antibody detects a band of approx. 200 kDa in lysates of cell lineJurkat.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- MYO5A (Myosin VA (MYO5A))
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别名
- Myosin-Va
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背景
- Myosin-Va has been implicated in the regulation of vesicle trafficking in neurons and melanocytes. It has been suggested that class V myosins associate with membrane vesicles through their C-terminal tails. Myosin V associates with synaptic vesicles and forms a stable complex with the synaptic vesicle membrane proteins, synaptobrevin II, and synaptophysin. The dilute Myo5a gene mutation in myosin Va leads to mental retardation, variable cellular immunodeficiency and impaired melanocyte function (pigmentary dilution), known as Griscelli syndrome in humans. Myosin Va regulates melanosome distribution along microfilaments. It is found in association with the centrosome at all stages of the cell cycle. In the interphase stage, myosin Va is found in pericentriolar material. During cell division, it is found in the cytoplasm and concentrates in a trail between migrating centrioles and in the mitotic spindle poles and spindle fibers.Synonyms: Dilute myosin heavy chain, MYH12, MYO5A, Myosin heavy chain 12, Myoxin, non-muscle
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分子量
- 215kDa (NP_000250.3).
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基因ID
- 4644
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NCBI登录号
- NP_000250
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UniProt
- Q9Y4I1
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途径
- Hormone Transport, Peptide Hormone Metabolism
抗原
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