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SNAP23 抗体 (Internal Region)

This 山羊 多克隆 antibody specifically detects SNAP23 in WB 和 EIA. It exhibits reactivity toward 人, 小鼠, 大鼠 和 Cow.
产品编号 ABIN499144
发货至: 中国
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Quick Overview for SNAP23 抗体 (Internal Region) (ABIN499144)

抗原

See all SNAP23 抗体
SNAP23 (Synaptosomal-Associated Protein, 23kDa (SNAP23))

适用

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人, 小鼠, 大鼠, Cow

宿主

  • 71
  • 4
  • 2
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山羊

克隆类型

  • 67
  • 12
多克隆

标记

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This SNAP23 antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

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    Internal Region

    序列

    C-QIKRITDKAD

    特异性

    This antibody is expected to recognize both reported isoforms (NP_003816.2 and NP_570710.1).

    交叉反应 (详细)

    Species reactivity (expected):Mouse, Rat, Bovine.
    Species reactivity (tested):Human.

    纯化方法

    Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.

    免疫原

    Peptide with sequence from the internal region of the protein sequence according to NP_003816.2 and NP_570710.1. Genename: SNAP23
  • 应用备注

    Peptide ELISA: Limit Dilution: 1/8000. Western blot: 0.1-0.3 μg/mL. This antibody detects a band of approx. 26 kDa Human Placentalysates.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    SNAP23 (Synaptosomal-Associated Protein, 23kDa (SNAP23))

    别名

    SNAP23

    背景

    Synaptosomal-associated proteins (SNAPs) are cytosolic proteins that play a key role in in the process of membrane fusion in intracellular vesicle trafficking. In eukaryotic cells, the SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) complex is critical to membrane docking and fusion and is believed to impart some degree of specificity between vesicle SNARE (v-SNARE) and target organelle SNARE (t-SNARE). In neurons and neuroendocrine cells, the SNARE complex consists of the integral membrane proteins VAMP (vesicle-associated membrane protein), syntaxin and SNAP-25. In non-neuronal tissue, a SNAP-25 homolog, SNAP-23, functionally replaces SNAP-25 in the SNARE complex. Studies show that VAMP, syntaxin and SNAP-23 are required for SNARE function and that this complex exists as a heterotrimer of the three proteins. In insulin signalling pathways, studies suggest that the translocation of GLUT4 in adipocytes requires that functional SNAP-23 be present in SNARE complexes.Synonyms: SNAP-23, Synaptosomal-associated protein 23, Vesicle-membrane fusion protein SNAP-23

    分子量

    23.4kDa (NP_003816.2

    基因ID

    8773

    NCBI登录号

    NP_003816

    UniProt

    O00161
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