FANCL 抗体 (Internal Region)
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Quick Overview for FANCL 抗体 (Internal Region) (ABIN499127)
抗原
See all FANCL 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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序列
- C-QNLKDVLEID FP
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特异性
- This antibody is expected to recognize both isoforms (NP_001108108.1, NP_060532.2).
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交叉反应 (详细)
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Species reactivity (expected):Mouse, Rat, Canine, Bovine.
Species reactivity (tested):Human. -
纯化方法
- Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.
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免疫原
- Peptide with sequence from the internal region of the protein sequence according to Human FANCL (NP_001108108.1 and NP_060532.2). Genename: FANCL
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应用备注
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Peptide ELISA: Limit Dilution: 1/16000. Western blot: 1-3 μg/mL. Detects a band of approx. 45 kDa in Human Bone Marrow lysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, pH 7.3, 0.02 % Sodium Azide, 0.5 % BSA
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- FANCL (Fanconi Anemia, Complementation Group L (FANCL))
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别名
- FANCL
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背景
- FANCL is a ubiquitin ligase protein that mediates ubiquitination of FANCD2, a key step in the DNA damage pathway.Synonyms: E3 ubiquitin-protein ligase FANCL, FAAP43, Fanconi anemia group L protein, Fanconi anemia-associated polypeptide of 43 kDa, PHF9
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分子量
- 43.4kDa (NP_001108108.1).
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基因ID
- 55120
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NCBI登录号
- NP_001108108
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UniProt
- Q9NW38
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途径
- DNA Damage Repair
抗原
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