TIAL1 抗体 (Internal Region)
Our Local Distributor
北京 101111
Quick Overview for TIAL1 抗体 (Internal Region) (ABIN499121)
抗原
See all TIAL1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Internal Region
-
序列
- C-SPEITTEDIK SAFAP
-
特异性
- This antibody is expected to recognize both isoforms (NP_003243.1, NP_001029097.1).
-
交叉反应 (详细)
-
Species reactivity (expected):Mouse, Canine, Bovine.
Species reactivity (tested):Human. -
纯化方法
- Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.
-
免疫原
- Peptide with sequence from the Internal region of Human TIAL1 (NP_003243.1 and NP_001029097.1) Genename: TIAL1
-
-
-
-
应用备注
-
Peptide ELISA: Limit Dilution: 1/64000. Western blot: 1-3 μg/mL. Approx 45 kDa band observed in lysates of cell line K562.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
浓度
- 0.5 mg/mL
-
缓冲液
- Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
-
- TIAL1 (TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1))
-
别名
- TIAL1
-
背景
- TIA1 is a member of an RNA binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15- kDa protein that is thought to be derived from the carboxyl terminus of the 40- kDa product by proteolytic processing.Synonyms: Nucleolysin TIAR, TIA-1-related protein
-
分子量
- 43.4 kDa (NP_001029097.1)
-
基因ID
- 7073
-
NCBI登录号
- NP_003243
-
UniProt
- Q01085
抗原
-