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IFI16 抗体

IFI16 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN499076
发货至: 中国
  • 抗原 See all IFI16 抗体
    IFI16 (Interferon, gamma-Inducible Protein 16 (IFI16))
    适用
    • 36
    • 3
    • 1
    宿主
    • 32
    • 4
    克隆类型
    • 34
    • 2
    多克隆
    标记
    • 21
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IFI16 antibody is un-conjugated
    应用范围
    • 36
    • 13
    • 13
    • 13
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB)
    特异性
    This antibody detects endogenous levels of IFI-16 protein. (region surrounding asn772)
    交叉反应 (详细)
    Species reactivity (tested):Human.
    纯化方法
    Affinity chromatography using epitope-specific immunogen
    纯度
    > 95 % (by SDS-PAGE)
    Top Product
    Discover our top product IFI16 Primary Antibody
  • 应用备注
    Western blot: 1: 500 - 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    IFI16 (Interferon, gamma-Inducible Protein 16 (IFI16))
    别名
    IFI16 / IFNGIP1 (IFI16 产品)
    别名
    IFNGIP1 antibody, PYHIN2 antibody, IFI16 antibody, Ifitm3l antibody, Ifitml antibody, interferon gamma inducible protein 16 antibody, interferon induced transmembrane protein 2 antibody, myeloid cell nuclear differentiation antigen-like protein antibody, interferon-activable protein 203 antibody, IFI16 antibody, Ifitm2 antibody, LOC100156073 antibody, LOC488622 antibody, Ifi16 antibody
    背景
    Interferon-gamma inducible protein 16 (IFI16) belongs to the HIN-200 family of transcriptional regulator linked to cell cycle regulation and differentiation by modulating the activities of multiple transcriptional factors, such as p53 and Rb. The HIN-200 (hematopoeitic interferon-inducible nuclear antigens with 200 amino acid repeat) family members contain a DNA binding domain, a transcriptional regulatory domain, DAPIN/PAAD domain associated with interferon response and a binding domain for BRCA1. IFI16 may have a role in the regulation of hematopoeitic cell differentiation and also be involved in DNA repair since it becomes a component of the DNA repair multi-protein BASC complex after UV-induced DNA damage. IFI16 is strongly induced by gamma interferon in vivo.Synonyms: Gamma-interferon-inducible protein Ifi-16, IFI-16, Interferon-inducible myeloid differentiation transcriptional activator
    分子量
    approx. 88 kDa
    基因ID
    3428
    NCBI登录号
    NP_005522
    UniProt
    Q16666
    途径
    Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Autophagy, Inflammasome
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