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GABRD 抗体

The 兔 多克隆 anti-GABRD antibody (ABIN499074) specifically detects GABRD in WB. The antibody is reactive with 人, 大鼠 和 小鼠 samples.
产品编号 ABIN499074
发货至: 中国
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Quick Overview for GABRD 抗体 (ABIN499074)

抗原

See all GABRD 抗体
GABRD (GABA A Receptor delta (GABRD))

适用

  • 28
  • 23
  • 17
  • 6
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
人, 大鼠, 小鼠

宿主

  • 30
  • 6

克隆类型

  • 30
  • 6
多克隆

标记

  • 24
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This GABRD antibody is un-conjugated

应用范围

  • 29
  • 17
  • 15
  • 10
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 特异性

    This antibody detects endogenous levels of GABAA Rδ protein. (region surrounding Asp181)

    交叉反应 (详细)

    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.

    纯化方法

    Affinity chromatography using epitope-specific immunogen

    纯度

    > 95 % (by SDS-PAGE)
  • 应用备注

    Western blot: 1: 500 - 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原

    GABRD (GABA A Receptor delta (GABRD))

    别名

    GABRD

    背景

    GAD-65 and GAD-67, glutamate decarboxylases function to catalyze the production of GABA (γ-aminobutyric acid). In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl-conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. Both GABAA and GABAC are ligand-gated ion channels, however, they are structurally and functionally distinct. Members of the GABAA receptor family include GABAA Rα1-6, GABAA R β1-3, GABAA Rγ1-3, GABAA Rδ, GABAA Rε, GABAA Rrho1 and GABAA Rrho2. The GABAB family is composed of GABAB R1α and GABAB R1β. GABA transporters have also been identified and include GABA T-1, GABA T-2 and GABA T-3 (also designated GAT-1, -2, and -3). The GABA transporters function to terminate GABA action.Synonyms: GABA A receptor subunit delta, Gamma-aminobutyric acid receptor subunit delta

    分子量

    approx. 51 kDa

    基因ID

    2563

    NCBI登录号

    NP_000806

    UniProt

    O14764
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