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C9 抗体

The 兔 多克隆 anti-C9 antibody (ABIN499053) specifically detects C9 in WB. The antibody is reactive with 人 samples.
产品编号 ABIN499053
发货至: 中国
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Quick Overview for C9 抗体 (ABIN499053)

抗原

See all C9 抗体
C9 (Complement Component C9 (C9))

适用

  • 80
  • 5
  • 3
  • 2
  • 2
  • 2

宿主

  • 68
  • 13
  • 2
  • 1

克隆类型

  • 60
  • 24
多克隆

标记

  • 39
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  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This C9 antibody is un-conjugated

应用范围

  • 62
  • 37
  • 31
  • 21
  • 15
  • 11
  • 11
  • 10
  • 7
  • 7
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  • 2
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Western Blotting (WB)
  • 特异性

    This antibody detects endogenous levels of C9 protein. (region surrounding His216)

    交叉反应 (详细)

    Species reactivity (tested):Human.

    纯化方法

    Affinity chromatography

    纯度

    > 95 % by SDS-PAGE
  • 应用备注

    Western Blot: 1/500 - 1/1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1,0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    C9 (Complement Component C9 (C9))

    别名

    Complement C9

    背景

    C9 is synthesised in the liver and monocytes, and is a plasma protein consisting of a single polypeptide chain of molecular weight 71 kDa. Normal plasma concentration is 60 mg/L. C9 forms part of the membrane attack complex (MAC) the cytolytic terminal complex of the complement pathways. C9 binds to the membrane associated C5b-8, binding of C9 to C5b-8 leads to the circular polymerisation of 12-18 C9 Molecules. This is the basis of the hydrophilic, proteinwalled, trans-membrane channel formed by the MAC, which leads to cell lysis and destruction.Synonyms: Complement 9, Complement component C9

    分子量

    approx. 70 kDa

    基因ID

    735

    NCBI登录号

    NP_001728

    UniProt

    P02748

    途径

    Complement System
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