Vitamin D Receptor 抗体
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北京 101111
Quick Overview for Vitamin D Receptor 抗体 (ABIN499023)
抗原
See all Vitamin D Receptor (VDR) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of VDR protein. (region surrounding Lys45)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity chromatography
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纯度
- > 95 % by SDS-PAGE
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anti-Vitamin D Receptor (VDR) (AA 65-180) antibody
VDR 适用: 人, 小鼠, 大鼠 WB, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Vitamin D Receptor (VDR) (Internal Region) antibodyVDR 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Vitamin D Receptor (VDR) (AA 1-300) antibodyVDR 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Vitamin D Receptor (VDR) (AA 1-427) antibodyVDR 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Vitamin D Receptor (VDR) (AA 377-402), (C-Term) antibodyVDR 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Vitamin D Receptor (VDR) (N-Term) antibodyVDR 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Vitamin D Receptor (VDR) (pSer208) antibodyVDR 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Vitamin D Receptor (VDR) (AA 266-422) antibodyVDR 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Vitamin D Receptor (VDR) antibodyVDR 适用: 人 WB, ELISA, IHC 宿主: 兔 Monoclonal 3C7 unconjugated Recombinant Antibody
anti-Vitamin D Receptor (VDR) (AA 1-428) antibodyVDR 适用: 人 ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2F4 unconjugated
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应用备注
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Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Vitamin D Receptor (VDR)
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别名
- Vitamin D3 Receptor / NR1I1
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物质类
- Chemical
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背景
- The vitamin D receptor (VDR), also known as the calcitriol receptor, and also known as NR1I1 (nuclear receptor subfamily 1, group I, member 1), is a member of the nuclear receptor family of transcription factors. Upon activation by vitamin D, the VDR forms a heterodimer with the retinoid-X receptor and binds to hormone response elements on DNA resulting in expression or trans-repression of specific gene products.It is an intracellular hormone receptor that specifically binds 1,25(OH)2D3 and mediates its effects. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer.Synonyms: 1, 25-dihydroxyvitamin D3 receptor, Nuclear receptor subfamily 1 group I member 1, VDR
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分子量
- approx. 48 kDa
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基因ID
- 7421
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NCBI登录号
- NP_000367
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UniProt
- P11473
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途径
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway
抗原
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