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Vitamin D Receptor 抗体

VDR 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN499023
发货至: 中国
  • 抗原 See all Vitamin D Receptor (VDR) 抗体
    Vitamin D Receptor (VDR)
    适用
    • 91
    • 53
    • 37
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 98
    • 11
    • 1
    • 1
    克隆类型
    • 92
    • 19
    多克隆
    标记
    • 56
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This Vitamin D Receptor antibody is un-conjugated
    应用范围
    • 85
    • 32
    • 26
    • 26
    • 16
    • 14
    • 13
    • 10
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody detects endogenous levels of VDR protein. (region surrounding Lys45)
    交叉反应 (详细)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    纯化方法
    Affinity chromatography
    纯度
    > 95 % by SDS-PAGE
    Top Product
    Discover our top product VDR Primary Antibody
  • 应用备注
    Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1,0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    Vitamin D Receptor (VDR)
    别名
    Vitamin D3 Receptor / NR1I1 (VDR 产品)
    别名
    vdrbeta antibody, vdr0 antibody, LOC100136219 antibody, NR1I1-B antibody, gb:dq017633 antibody, vdr-b antibody, Ci-VDR-b antibody, VDR antibody, LOC100221284 antibody, vdr-A antibody, xVDR antibody, Nr1i1 antibody, vdr antibody, NR1I1 antibody, PPP1R163 antibody, vitamin D (1,25- dihydroxyvitamin D3) receptor antibody, vitamin D receptor antibody, vitamin D3 receptor A antibody, vitamin D receptor b antibody, nuclear receptor VDR-b antibody, vitamin D (1,25- dihydroxyvitamin D3) receptor L homeolog antibody, vitamin D (1,25-dihydroxyvitamin D3) receptor antibody, vitamin D receptor a antibody, vdr antibody, vdr0 antibody, VDR antibody, LOC100136219 antibody, vdrb antibody, vdr-b antibody, vdr.L antibody, Vdr antibody, vdra antibody
    物质类
    Chemical
    背景
    The vitamin D receptor (VDR), also known as the calcitriol receptor, and also known as NR1I1 (nuclear receptor subfamily 1, group I, member 1), is a member of the nuclear receptor family of transcription factors. Upon activation by vitamin D, the VDR forms a heterodimer with the retinoid-X receptor and binds to hormone response elements on DNA resulting in expression or trans-repression of specific gene products.It is an intracellular hormone receptor that specifically binds 1,25(OH)2D3 and mediates its effects. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer.Synonyms: 1, 25-dihydroxyvitamin D3 receptor, Nuclear receptor subfamily 1 group I member 1, VDR
    分子量
    approx. 48 kDa
    基因ID
    7421
    NCBI登录号
    NP_000367
    UniProt
    P11473
    途径
    Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway
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