MAPKAP Kinase 2 抗体
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Quick Overview for MAPKAP Kinase 2 抗体 (ABIN498988)
抗原
See all MAPKAP Kinase 2 (MAPKAPK2) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of MAPKAPK-2 protein. (region surrounding asn218)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity chromatography
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纯度
- > 95 % by SDS-PAGE
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anti-Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 (MAPKAPK2) (AA 139-367) antibody
MAPKAPK2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 (MAPKAPK2) (AA 302-400) antibodyMAPKAPK2 适用: 人 WB, ELISA, IF, IP, IHC (p), PLA 宿主: 小鼠 Monoclonal 2B3 unconjugated
anti-Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 (MAPKAPK2) (AA 266-352) antibodyMAPKAPK2 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3B8 unconjugated
anti-Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 (MAPKAPK2) antibodyKD Validated MAPKAPK2 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB2950 unconjugated Recombinant Antibody
anti-Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 (MAPKAPK2) (Internal Region) antibodyVerified MAPKAPK2 适用: 人, 小鼠 WB, IHC, ELISA, IP 宿主: 山羊 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 (MAPKAPK2) (AA 301-400) antibodyMAPKAPK2 适用: 大鼠 WB, ELISA, IF (p), IHC (p), IF (cc), FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 (MAPKAPK2) (pThr222) antibodyMAPKAPK2 适用: 小鼠, 大鼠, 猴 WB, ELISA, IF (p), IHC (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 (MAPKAPK2) (pThr334) antibodyMAPKAPK2 适用: 人, 小鼠, 大鼠 IF (p), IHC (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 (MAPKAPK2) (AA 266-352) antibodyMAPKAPK2 适用: 人 WB, ELISA, IF, IP 宿主: 小鼠 Monoclonal 1F9 unconjugated
anti-Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 (MAPKAPK2) (AA 1-400) antibodyMAPKAPK2 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- MAPKAP Kinase 2 (MAPKAPK2) (Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 (MAPKAPK2))
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别名
- MAPKAP Kinase-2
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背景
- MAP kinase activated protein kinase 2 (MAPKAP Kinase 2), also known as p45 hsp27 kinase, is a 45-54 kDa serine/threonine protein kinase that contains a proline rich sequence and two putative SH3 binding sites. MAPKAP Kinase 2 is activated in response to stress, IL1 and TNF, possibly catalyzed by p38/Hog dependent phosphorylation. One of the major substrates of MAPKAP Kinase 2 is hsp27, which stimulates actin polymerization in order to facilitate recovery from destruction of cytoskeleton during cellular stresses. MAPKAP2 is implicated in several disorders including ischemic brain injury and heart failure and has been shown to be important in regulating stress resistance and the production of TNF alpha.Synonyms: MAP kinase-activated protein kinase 2, MAPK-activated protein kinase 2, MAPKAP kinase 2, MAPKAPK-2, MAPKAPK2, MK2
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分子量
- approx. 46 kDa
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基因ID
- 9261
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NCBI登录号
- NP_004750
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UniProt
- P49137
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途径
- MAPK Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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