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CrkL 抗体 (pTyr207)
CRKL
适用: 人, 小鼠, 大鼠
IHC (p)
宿主: 兔
Polyclonal
unconjugated
CrkL抗体详情
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抗原
See all CrkL (CRKL) 抗体
CrkL (CRKL)
(V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL))
抗原表位
All epitopes for CrkL 抗体
pTyr207
适用
All reactivities for CrkL 抗体
人, 小鼠, 大鼠
宿主
All hosts for CrkL 抗体
兔
克隆类型
All clonalities for CrkL 抗体
多克隆
标记
All conjugates for CrkL 抗体
This CrkL antibody is un-conjugated
应用范围
All applications for CrkL 抗体
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
特异性
This antibody detects endogenous levels of p-CrkL protein only when phosphorylated at Try207.
交叉反应 (详细)
Species reactivity (expected):Mouse and Rat. Species reactivity (tested):Human.
纯化方法
Affinity chromatography
纯度
> 95 % by SDS-PAGE
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Alternatives
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使用细节
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应用备注
Immunohistochemistry: 1/50 - 1/200. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
限制
仅限研究用
贮存及处理
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浓度
1,0 mg/mL
缓冲液
Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
储存液
Sodium azide
注意事项
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项
Avoid repeated freezing and thawing.
储存条件
4 °C/-20 °C
储存方法
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
CrkL目标详情
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抗原
CrkL (CRKL)
(V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL))
别名
CRKL (CRKL 产品 )
别名
CRKL antibody, wu:fa55g05 antibody, wu:fj60e01 antibody, zgc:63469 antibody, 1110025F07Rik antibody, AA589403 antibody, AI325100 antibody, Crkol antibody, CRK like proto-oncogene, adaptor protein antibody, v-crk avian sarcoma virus CT10 oncogene homolog-like antibody, CRKL antibody, crkl antibody, Crkl antibody
背景
Crk, is a transformation-specific protein that induces elevation of cellular phosphotyrosine levels, but lacks tyrosine kinase activity itself. A second protein, Nck, consists solely of three SH3 domains and one SH2 domain, while GRB2 contains an SH2 domain flanked on both sides by SH3 domains. A member of this protein class, Crk-L, is encoded by a gene located on chromosome 22, band 11, centromeric of the chronic myelogenous leukemia breakpoint region. Crk-L encodes a 303 amino acid protein with one SH2 and two SH3 domains, and a predicted molecular weight of 36 kDa.Synonyms: Crk-like protein, v-crk avian sarcoma virus CT10 oncogene homolog-like
分子量
approx. 39 kDa
基因ID
1399
NCBI登录号
NP_005198
UniProt
P46109
途径
Interferon-gamma Pathway , Neurotrophin Signaling Pathway , Signaling of Hepatocyte Growth Factor Receptor
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