PGC 抗体
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北京 101111
Quick Overview for PGC 抗体 (ABIN498676)
抗原
See all PGC 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of Pepsin C protein. (region surrounding Phe306)
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交叉反应 （详细）
- Species reactivity (tested):Human.
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纯化方法
- Affinity chromatography
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纯度
- > 95 % by SDS-PAGE
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anti-Pepsinogen C (PGC) (AA 100-200) antibody
PGC 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Pepsinogen C (PGC) (AA 17-392) antibodyPGC 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pepsinogen C (PGC) (Internal Region) antibodyPGC 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Pepsinogen C (PGC) (AA 61-388) antibodyPGC 适用: 人 WB, IHC, IP, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Pepsinogen C (PGC) (AA 1-388) antibodyPGC 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Pepsinogen C (PGC) (AA 1-388) antibodyPGC 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Pepsinogen C (PGC) (AA 17-392) antibodyPGC 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pepsinogen C (PGC) (AA 21-120) antibodyPGC 适用: 人 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Pepsinogen C (PGC) (pSer15) antibodyPGC 适用: 植物 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- PGC (Pepsinogen C (PGC))
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别名
- Pepsinogen Group II
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背景
- Pepsin is one of the main proteolytic enzymes secreted by the gastric mucosa. Pepsin consists of a single polypeptide chain and arises from its precursor, Pepsinogen, by removal of a 41 amino acid segment from the amino end. Pepsinogen is synthesized in the stomach lining, hydrochloric acid, also produced by the gastric mucosa, is necessary to convert the inactive enzyme and to maintain the optimum acidity ( pH 1-3) for Pepsin function. Pepsin is particularly effective in cleaving peptide bonds involving aromatic amino acids. It shows extremely broad specificity, and although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent. The amino acid composition of Pepsin C differs from those of Pepsinogen and Pepsin, especially in the content of basic amino acids, glutamic acid, aspartic acid, leucine and isoleucine.Synonyms: Gastricsin, PGC, Pepsinogen C, Progastricsin
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分子量
- approx. 42 kDa
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基因ID
- 5225
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NCBI登录号
- NP_002621
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UniProt
- P20142
抗原
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