CD3D 抗体 (Chain delta)
Our Local Distributor
北京 101111
Quick Overview for CD3D 抗体 (Chain delta) (ABIN498559)
抗原
See all CD3D 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Chain delta
-
特异性
- This antibody detects endogenous levels of CD3-δ protein. (region surrounding Thr56)
-
交叉反应 (详细)
- Species reactivity (tested):Human.
-
纯化方法
- Affinity chromatography using epitope-specific immunogen
-
纯度
- > 95 % (by SDS-PAGE)
-
-
-
-
应用备注
-
Western blot: 1: 500 - 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
浓度
- 1.0 mg/mL
-
缓冲液
- Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
-
-
- CD3D (CD3d Molecule, delta (CD3-TCR Complex) (CD3D))
-
别名
- CD3 delta Chain
-
背景
- The CD3 complex mediates signal transduction. Defects in CD3D are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (T-B+NK+ SCID) [MIM:608971]. A form of severe combined immunodeficiency (SCID), a genetically and clinically heterogeneous group of rare congenital disorders characterized by impairment of both humoral and cell-mediated immunity, leukopenia, and low or absent antibody levels. Patients present in infancy recurrent, persistent infections by opportunistic organisms. The common characteristic of all types of SCID is absence of T-cell-mediated cellular immunity due to a defect in T-cell development.Synonyms: CD3D, T-cell surface glycoprotein CD3 delta chain, T3D
-
分子量
- approx. 24 kDa
-
基因ID
- 915
-
NCBI登录号
- NP_000723
-
UniProt
- P04234
-
途径
- TCR Signaling, CXCR4-mediated Signaling Events
抗原
-