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Cathepsin B 抗体

The 兔 多克隆 anti-Cathepsin B antibody (ABIN498549) specifically detects Cathepsin B in WB 和 IHC (p). The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN498549
发货至: 中国
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Quick Overview for Cathepsin B 抗体 (ABIN498549)

抗原

See all Cathepsin B (CTSB) 抗体
Cathepsin B (CTSB)

适用

  • 80
  • 38
  • 37
  • 7
  • 1
人, 小鼠, 大鼠

宿主

  • 77
  • 19
  • 3
  • 1
  • 1

克隆类型

  • 55
  • 46
多克隆

标记

  • 45
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  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Cathepsin B antibody is un-conjugated

应用范围

  • 78
  • 40
  • 29
  • 23
  • 22
  • 21
  • 19
  • 13
  • 13
  • 6
  • 3
  • 3
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 特异性

    This antibody detects endogenous levels of Cathepsin B protein. (region surrounding asn217)

    交叉反应 (详细)

    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.

    纯化方法

    Affinity Chromatography using epitope-specific immunogen.
  • 应用备注

    Western Blot: 1/500approx. 1/1000. Immunohistochemistry on Paraffin Sections: 1/50approx. 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    Cathepsin B (CTSB)

    别名

    Cathepsin B

    背景

    The cathepsin family of proteolytic enzymes contains several diverse classes of proteases. The cysteine protease class comprises cathepsins B, L, H, K, S and O. The aspartyl protease class is composed of cathepsins D and E. cathepsin G is in the serine protease class. Most cathepsins are lysosomal and each is involved in cellular metabolism, participating in various events such as peptide biosynthesis and protein degradation. cathepsin B is expressed in luminal epithelial cells, indicating that cathepsin B is a marker for secretory cell death.Synonyms: APP secretase, APPS, CPSB, CTSB, Cathepsin B1

    分子量

    approx. 36 kDa

    基因ID

    1508

    NCBI登录号

    NP_001899

    UniProt

    P07858

    途径

    Activation of Innate immune Response, Toll-Like Receptors Cascades
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