KRT14 抗体
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北京 101111
Quick Overview for KRT14 抗体 (ABIN498520)
抗原
See all KRT14 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This detects endogenous levels of Cytokeratin 14 protein.(region surrounding Tyr151)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity chromatography using epitope-specific immunogen
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纯度
- > 95 % (by SDS-PAGE)
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anti-Keratin 14 (KRT14) antibody
KRT14 适用: 人 IHC, WB, IF, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Keratin 14 (KRT14) antibodyKRT14 适用: 人, 大鼠, 小鼠 IHC, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Keratin 14 (KRT14) (AA 1-484) antibodyKRT14 适用: 小鼠 IHC, WB, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Keratin 14 (KRT14) (C-Term) antibodyKRT14 适用: 人 IHC, IF, FACS 宿主: 小鼠 Monoclonal LL002 unconjugated
anti-Keratin 14 (KRT14) (AA 351-472) antibodyKRT14 适用: 人, 大鼠, 小鼠, Pig IHC, FACS 宿主: 小鼠 Monoclonal KRT14-2375 unconjugated
anti-Keratin 14 (KRT14) (C-Term) antibodyKRT14 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Keratin 14 (KRT14) antibodyKRT14 适用: 人, 大鼠, Pig, 犬 IHC, WB, FACS, ICC, IHC (fro) 宿主: 小鼠 Monoclonal RCK107 unconjugated
anti-Keratin 14 (KRT14) (C-Term) antibodyKRT14 适用: 人 IHC, WB, FACS, ICC, IP 宿主: 小鼠 Monoclonal LL002 unconjugated Recombinant Antibody
anti-Keratin 14 (KRT14) (C-Term) antibodyKRT14 适用: 人 IHC, WB, FACS, ICC, IP 宿主: 小鼠 Monoclonal LL002 unconjugated Recombinant Antibody
anti-Keratin 14 (KRT14) antibodyKRT14 适用: 人 IHC, WB 宿主: 兔 Monoclonal unconjugated
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应用备注
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Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- KRT14 (Keratin 14 (KRT14))
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别名
- Cytokeratin 14
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背景
- Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed in pairs in both keratinized and non-keratinized epithelial tissue, where they constitute up to 85 % of mature keratinocytes in the vertebrate epidermis. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. The alpha-helical coiled-coil dimers associate laterally end-to-end to form 10-nm diameter filaments. Cytokeratins are useful markers of tissue differentiation, and in addition they aid in the characterization of malignant tumors. In Bowen's disease, the characteristic malignancy of the epidermis exhibits distinct expression patterns of cytokeratin 14. The gene encoding human cytokeratin 14 maps to chromosome 17q12- 21. Mutations in this gene lead to epidermolysis bullosa simplex, an inheritied skin disorder characterized by skin blistering due to basal keratinocyte fragility.Synonyms: CK14, Cytokeratin-14, K14, KRT14, Keratin 14, Keratin Type I Cytoskeletal 14
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分子量
- approx. 52 kDa
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基因ID
- 3861
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NCBI登录号
- NP_000517
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UniProt
- P02533
抗原
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