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Interferon gamma 抗体

The 兔 多克隆 anti-Interferon gamma antibody (ABIN498507) specifically detects Interferon gamma in WB 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN498507
发货至: 中国
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Quick Overview for Interferon gamma 抗体 (ABIN498507)

抗原

See all Interferon gamma (IFNG) 抗体
Interferon gamma (IFNG)

适用

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宿主

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克隆类型

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多克隆

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This Interferon gamma antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 特异性

    This antibody detects endogenous levels of IFN-gamma protein. (region surrounding Gln69)

    交叉反应 (详细)

    Species reactivity (tested):Human.

    纯化方法

    Affinity chromatography

    纯度

    > 95 % by SDS-PAGE
  • 应用备注

    Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1,0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    Interferon gamma (IFNG)

    别名

    IFNG / Interferon gamma

    背景

    Interferon (IFN)-gamma is an antiviral and antiparasitic agent produced by CD4+/ CD8+ lymphocytes and natural killer cells that undergo activation by antigens, mitogens or alloantigens. IFN-gamma production modulates T cell growth and differentiation and inhibits the growth of B cells. Synthesis of IFN-gamma is inducible by IL-2, FGF and EGF. The active form of IFN-gamma is a homodimer with each subunit containing six helices. The dimeric structure of human IFN-gamma is stabilized by non-covalent interactions through the interface of the helices. IFN-gamma tranlsated precursor is 166 amino acids, including the 23 amino acid secretory sequence. 20 kDa and 25 kDa forms exist due to variable glycosylation, 40-60 kDa forms are observable under non-denaturing conditions as dimers and tetramers.Synonyms: IFN-gamma, gamma IFN

    分子量

    approx. 22 kDa

    基因ID

    3458

    NCBI登录号

    NP_000610

    UniProt

    P01579

    途径

    Interferon-gamma Pathway, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy
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