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- 抗原 See all PLAU 抗体
- PLAU (Plasminogen Activator, Urokinase (PLAU))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PLAU antibody is un-conjugated
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应用范围
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody detects endogenous levels of uPA protein. (region surrounding Leu239)
- 交叉反应 （详细）
- Species reactivity (tested):Human.
- 纯化方法
- Affinity chromatography
- 纯度
- > 95 % by SDS-PAGE
- Top Product
- Discover our top product PLAU Primary Antibody
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anti-Plasminogen Activator, Urokinase (PLAU) (AA 60-90), (N-Term) antibody
PLAU 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB04087 unconjugated
anti-Plasminogen Activator, Urokinase (PLAU) (C-Term) antibodyVerified PLAU 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Plasminogen Activator, Urokinase (PLAU) (AA 396-426) antibodyPLAU 适用: 人 WB, ELISA, IHC, FACS, IF 宿主: 兔 Polyclonal unconjugated
anti-Plasminogen Activator, Urokinase (PLAU) (AA 60-90) antibodyPLAU 适用: 人, 小鼠 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Plasminogen Activator, Urokinase (PLAU) (AA 180-433) antibodyPLAU 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Plasminogen Activator, Urokinase (PLAU) (AA 16-115) antibodyPLAU 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3B8 unconjugated
anti-Plasminogen Activator, Urokinase (PLAU) antibodyPLAU 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Plasminogen Activator, Urokinase (PLAU) (AA 396-426), (C-Term) antibodyPLAU 适用: 人 WB, FACS, IHC (p), IF 宿主: 兔 Polyclonal RB04089-04090 unconjugated
anti-Plasminogen Activator, Urokinase (PLAU) (AA 17-432) antibodyPLAU 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Plasminogen Activator, Urokinase (PLAU) (AA 21-173) antibodyPLAU 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1,0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- PLAU (Plasminogen Activator, Urokinase (PLAU))
- 别名
- uPA / PLAU (PLAU 产品)
- 别名
- PLAU antibody, u-PA antibody, ATF antibody, BDPLT5 antibody, QPD antibody, UPA antibody, URK antibody, uPA antibody, UPAM antibody, plasminogen activator, urokinase antibody, urokinase-type plasminogen activator antibody, PLAU antibody, CpipJ_CPIJ002131 antibody, CpipJ_CPIJ006543 antibody, CpipJ_CPIJ013396 antibody, CpipJ_CPIJ013623 antibody, Plau antibody
- 背景
- UPA (urokinase-type plasminogen activator) and tPA (tissue plasminogen activator) are serine proteases that are members of the trypsin family, and they are essential to the intrinsic coagulation system. tPA is primarily involved in fibrinolysis, whereas uPA principally mediates cell migration and tissue remodeling processes. uPA and tPA are responsible for cleaving plasminogen, a large serum β-globulin that is deposited on the Fibrin strands within a thrombus. uPA and tPA preferentially target plasminogen at the Arg-Val bond to produce plasmin (also designated fibrinolysin), which is a trypsin-like enzyme that acts on Arg-Lys bonds in Fibrin and Fibrinogen and contributes to the systematic activation of the coagulation cascade. uPA and tPA each consist of two chains that are designated A and B. The A chain of uPA can be cleaved, resulting in low and high molecular mass forms. uPA and tPA are regulated by the serpin family members PAI-1 and PAI-2, which are serine proteinase inhibitors that complex with uPA, tPA and other targeted proteinases and then slowly disassociate to produce cleaved species that fold into stable inactive conformations.Synonyms: U-plasminogen activator, Urokinase, Urokinase-type plasminogen activator, Urokinase-type plasminogen activator chain B, Urokinase-type plasminogen activator long chain A, Urokinase-type plasminogen activator short chain A
- 分子量
- approx. 48 kDa
- 基因ID
- 5328
- NCBI登录号
- NP_001138503
- UniProt
- P00749
- 途径
- Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy, Smooth Muscle Cell Migration
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