DIDO1 抗体
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北京 101111
Quick Overview for DIDO1 抗体 (ABIN498449)
抗原
See all DIDO1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of DIDO1 / Dio-1 protein. (region surrounding Ser186)
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交叉反应 （详细）
- Species reactivity (tested):Human, Mouse.
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纯化方法
- Affinity Chromatography using epitope-specific immunogen
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anti-Death Inducer-Obliterator 1 (DIDO1) (AA 321-420) antibody
DIDO1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3B1 unconjugated
anti-Death Inducer-Obliterator 1 (DIDO1) (AA 1-300) antibodyDIDO1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Death Inducer-Obliterator 1 (DIDO1) (AA 1-544) antibodyDIDO1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Death Inducer-Obliterator 1 (DIDO1) (AA 72-121) antibodyDIDO1 适用: 人, 豚鼠, 兔, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Death Inducer-Obliterator 1 (DIDO1) (C-Term) antibodyDIDO1 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Death Inducer-Obliterator 1 (DIDO1) (N-Term) antibodyDIDO1 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Death Inducer-Obliterator 1 (DIDO1) (AA 321-420) antibodyDIDO1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Death Inducer-Obliterator 1 (DIDO1) (N-Term) antibodyDIDO1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Death Inducer-Obliterator 1 (DIDO1) (AA 480-529) antibodyDIDO1 适用: 人, 小鼠, 大鼠, 豚鼠, 兔, 猴, 斑马鱼, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-Death Inducer-Obliterator 1 (DIDO1) (N-Term) antibodyDIDO1 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 兔, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200. Immunofluorescence: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- DIDO1 (Death Inducer-Obliterator 1 (DIDO1))
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别名
- DIDO1
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背景
- DIDO1 / Dio-1 (Death Inducer-Obliterator-1) is a putative transcription factor that contains two zinc finger motifs. Dio-1 translocates to the nucleus, and activates apoptosis during limb development. Programmed cell death, a highly regulated form of apoptosis, plays an important role in determining the amount of tissue, the shape, and the definition of each digit during limb development. Dio-1 expression is upregulated when an apoptotic signal is detected, and subsequently apoptosis is induced. This process is similar to the expression of NFκB and NGF in response to external signals. Dio-1 expression is suppressed by caspase inhibitors and Bcl-2 expression. This supports the theory that Dio-1 functions in the onset of programmed cell death.Synonyms: C20orf158, DATF1, Death-inducer obliterator 1, KIAA0333
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分子量
- approx. 244 kDa
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基因ID
- 11083
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NCBI登录号
- NP_071388
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UniProt
- Q9BTC0
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途径
- Hormone Activity
抗原
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