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DIDO1 抗体

DIDO1 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN498449
发货至: 中国
  • 抗原 See all DIDO1 抗体
    DIDO1 (Death Inducer-Obliterator 1 (DIDO1))
    适用
    • 29
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    • 1
    • 1
    人, 小鼠
    宿主
    • 23
    • 6
    克隆类型
    • 26
    • 3
    多克隆
    标记
    • 22
    • 1
    • 1
    • 1
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    This DIDO1 antibody is un-conjugated
    应用范围
    • 20
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    • 2
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    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody detects endogenous levels of DIDO1 / Dio-1 protein. (region surrounding Ser186)
    交叉反应 (详细)
    Species reactivity (tested):Human, Mouse.
    纯化方法
    Affinity Chromatography using epitope-specific immunogen
    Top Product
    Discover our top product DIDO1 Primary Antibody
  • 应用备注
    Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200. Immunofluorescence: 1/50 - 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    DIDO1 (Death Inducer-Obliterator 1 (DIDO1))
    别名
    DIDO1 (DIDO1 产品)
    别名
    5DI antibody, TXDI1 antibody, BYE1 antibody, C20orf158 antibody, DATF-1 antibody, DATF1 antibody, DIDO2 antibody, DIDO3 antibody, DIO-1 antibody, DIO1 antibody, dJ885L7.8 antibody, 6720461J16Rik antibody, C530043I07 antibody, D130048F08Rik antibody, Datf1 antibody, Dido2 antibody, Dido3 antibody, mKIAA0333 antibody, DIDO1 antibody, datf1l antibody, fi35b04 antibody, wu:fi35b04 antibody, zgc:158157 antibody, DKFZp469J1523 antibody, bye1 antibody, dio1 antibody, datf1 antibody, dido2 antibody, dido3 antibody, dio-1 antibody, iodothyronine deiodinase 1 antibody, death inducer-obliterator 1 antibody, death inducer-obliterator 1 L homeolog antibody, DIO1 antibody, DIDO1 antibody, Dido1 antibody, dido1.L antibody, dido1 antibody
    背景
    DIDO1 / Dio-1 (Death Inducer-Obliterator-1) is a putative transcription factor that contains two zinc finger motifs. Dio-1 translocates to the nucleus, and activates apoptosis during limb development. Programmed cell death, a highly regulated form of apoptosis, plays an important role in determining the amount of tissue, the shape, and the definition of each digit during limb development. Dio-1 expression is upregulated when an apoptotic signal is detected, and subsequently apoptosis is induced. This process is similar to the expression of NFκB and NGF in response to external signals. Dio-1 expression is suppressed by caspase inhibitors and Bcl-2 expression. This supports the theory that Dio-1 functions in the onset of programmed cell death.Synonyms: C20orf158, DATF1, Death-inducer obliterator 1, KIAA0333
    分子量
    approx. 244 kDa
    基因ID
    11083
    NCBI登录号
    NP_071388
    UniProt
    Q9BTC0
    途径
    Hormone Activity
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