CIITA 抗体
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北京 101111
Quick Overview for CIITA 抗体 (ABIN498419)
抗原
See all CIITA 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of CIITA protein. (region surrounding Thr740)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity chromatography
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纯度
- > 95 % by SDS-PAGE
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anti-Class II, Major Histocompatibility Complex, Transactivator (CIITA) (AA 945-1130) antibody
CIITA 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Class II, Major Histocompatibility Complex, Transactivator (CIITA) (Internal Region) antibodyCIITA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Class II, Major Histocompatibility Complex, Transactivator (CIITA) (C-Term) antibodyCIITA 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Class II, Major Histocompatibility Complex, Transactivator (CIITA) (AA 841-890) antibodyCIITA 适用: 小鼠, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-Class II, Major Histocompatibility Complex, Transactivator (CIITA) (C-Term) antibodyCIITA 适用: 小鼠, 大鼠, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-Class II, Major Histocompatibility Complex, Transactivator (CIITA) (AA 34-1038) antibodyCIITA 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Class II, Major Histocompatibility Complex, Transactivator (CIITA) (AA 1-333) antibodyCIITA 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- CIITA (Class II, Major Histocompatibility Complex, Transactivator (CIITA))
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别名
- CIITA / C2TA
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背景
- The transactivator CIITA regulates basal and interferon-induced expression of MHC class II genes. CIITA restores expression of all MHC II gene expression in mutant cells and corrects regulatory defects of those genes. Activation is via the proximal promoter. No DNA binding of in vitro translated CIITA was detected. CIITA may act in a coactivator-like fashion through protein-protein interactions by contacting factors binding to the proximal MHC class II promoter, to elements of the transcription machinery, or both. Alternatively it may activate HLA class II transcription by modifying proteins that bind to the MHC class II promoter.Synonyms: MHC class II transactivator, MHC2TA
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分子量
- approx. 123 kDa
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基因ID
- 4261
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NCBI登录号
- NP_000237
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UniProt
- P33076
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途径
- Cancer Immune Checkpoints
抗原
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