c-MYC 抗体
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北京 101111
Quick Overview for c-MYC 抗体 (ABIN498414)
抗原
See all c-MYC (MYC) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of c-Myc protein. (region surrounding Lys422)
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交叉反应 （详细）
- Species reactivity (tested):Human, Mouse.
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纯化方法
- Affinity chromatography
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纯度
- > 95 % by SDS-PAGE
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anti-Myc Proto-Oncogene protein (MYC) (AA 330-439) antibody
MYC 适用: 人 WB, IF, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1G7 unconjugated
anti-Myc Proto-Oncogene protein (MYC) (Center) antibodyMYC 适用: 人, 小鼠 WB, IF, IP, ICC, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Myc Proto-Oncogene protein (MYC) (AA 31-80) antibodyMYC 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Myc Proto-Oncogene protein (MYC) (pSer62) antibodyMYC 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-Myc Proto-Oncogene protein (MYC) (pThr58) antibodyMYC 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ELISA, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Myc Proto-Oncogene protein (MYC) (AA 360-440) antibodyMYC 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Myc Proto-Oncogene protein (MYC) (AA 101-200) antibodyMYC 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), ICC, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Myc Proto-Oncogene protein (MYC) (N-Term) antibodyMYC 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-Myc Proto-Oncogene protein (MYC) antibodyMYC 适用: 人 ELISA 宿主: 小鼠 Monoclonal 7E10 unconjugated
anti-Myc Proto-Oncogene protein (MYC) (AA 257-439) antibodyMYC 适用: 人, 小鼠, 大鼠 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200. Immunfluorescence: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))
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别名
- C-Myc
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背景
- The c-Myc protein is a transcription factor, which is encoded by the c-Myc gene on human chromosome 8q24. c-Myc is commonly activated in a variety of tumor cells and plays an important role in cellular proliferation, differentiation, apoptosis and cell cycle progression. The phosphorylation of c-Myc has been investigated and previous studies have suggested a functional association between phosphorylation at Thr58/Ser62 by glycogen synthase kinase 3, cyclin dependent kinase, ERK2 and C-Jun N terminal Kinase (JNK) in cell proliferation and cell cycle regulation. Studies also have shown that c-Myc is essential for tumor cell development in vasculogenesis and angiogenesis that distribute blood throughout the cells, and which brought extensive attention in the development of new therapeutic approach for cancer treatment.Synonyms: BHLHE39, Class E basic helix-loop-helix protein 39, Myc proto-oncogene protein, Transcription factor p64
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分子量
- approx. 50 to 65 kDa
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基因ID
- 4609
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NCBI登录号
- NP_002458
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UniProt
- P01106
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途径
- p53 Pathway, Cell Division Cycle, Sensory Perception of Sound, Transition Metal Ion Homeostasis, Mitotic G1-G1/S Phases, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Warburg Effect
抗原
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