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CDC7 抗体

This 兔 多克隆 antibody specifically detects CDC7 in WB 和 IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN498406
发货至: 中国
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Quick Overview for CDC7 抗体 (ABIN498406)

抗原

See all CDC7 抗体
CDC7 (Cell Division Cycle 7 (CDC7))

适用

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宿主

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克隆类型

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多克隆

标记

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This CDC7 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 特异性

    This antibody detects endogenous levels of Cdc7 protein. (region surrounding Phe35)

    交叉反应 (详细)

    Species reactivity (tested):Human.

    纯化方法

    Affinity chromatography

    纯度

    > 95 % by SDS-PAGE
  • 应用备注

    Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1,0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    CDC7 (Cell Division Cycle 7 (CDC7))

    别名

    CDC7

    背景

    DNA replication in eukaryotic cells is dependent on the phosphorylation of the pre-replicative complex (preRC) at the origin of replication. Two complexes of proteins mediate this event, the cyclin dependent kinase (CDK) complex, and the Cdc7 kinase-ASK complex. Human Cdc7 kinase consists of 574 amino acids with a molecular weight of 55 kDa. The activity of Cdc7 kinase oscillates during cell cycle. The major targets of Cdc7 kinase are proteins that belong to the MCM complex (mini chromosome maintenance proteins). Cdc7 kinase was also found to be important in meiosis, checkpoint responses, maintenance of chromosome structure, and repair.Synonyms: CDC7-related kinase, CDC7L1, Cell division cycle 7-related protein kinase, HsCdc7, huCdc7

    分子量

    approx. 70 kDa

    基因ID

    8317

    NCBI登录号

    NP_001127891

    UniProt

    O00311

    途径

    Mitotic G1-G1/S Phases, DNA Replication
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