Cyclin D1 抗体
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北京 101111
Quick Overview for Cyclin D1 抗体 (ABIN498398)
抗原
See all Cyclin D1 (CCND1) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of Cyclin D1 protein (region surrounding Asp86)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity chromatography
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纯度
- > 95 % by SDS-PAGE
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anti-Cyclin D1 (CCND1) (AA 61-110) antibody
CCND1 适用: 人, 小鼠, 大鼠, Cow, 兔, 绵羊 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Cyclin D1 (CCND1) (C-Term) antibodyCCND1 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Cyclin D1 (CCND1) (AA 167-295) antibodyCCND1 适用: 人 IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 3B6G3 unconjugated
anti-Cyclin D1 (CCND1) (AA 1-295) antibodyCCND1 适用: 人, 小鼠 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 1F7F5 unconjugated
anti-Cyclin D1 (CCND1) (AA 68-97) antibodyCCND1 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB8066 unconjugated
anti-Cyclin D1 (CCND1) (C-Term) antibodyCCND1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin D1 (CCND1) antibodyKD Validated CCND1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB735 unconjugated Recombinant Antibody
anti-Cyclin D1 (CCND1) antibodyCCND1 适用: 人 WB, IHC, FACS, IF 宿主: 小鼠 Monoclonal DCS-6 unconjugated
anti-Cyclin D1 (CCND1) (C-Term) antibodyCCND1 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Cyclin D1 (CCND1) (AA 1-295) antibodyCCND1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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: "Unveiling the optimal parameters for cellulolytic characteristics of Talaromyces verruculosus SGMNPf3 and its secretory enzymes." in: Journal of applied microbiology, Vol. 119, Issue 1, pp. 88-98, (2016) (PubMed).
: "High-throughput screening system for inhibitors of human Heat Shock Factor 2." in: Cell stress & chaperones, Vol. 20, Issue 5, pp. 833-41, (2016) (PubMed).
: "Gastric adenocarcinoma of the fundic gland type shares common genetic and phenotypic features with pyloric gland adenoma." in: Pathology international, Vol. 63, Issue 6, pp. 318-25, (2015) (PubMed).
: "Potential of UCHL1 as biomarker for destruction of pancreatic beta cells." in: Journal of proteomics, Vol. 117, pp. 156-67, (2015) (PubMed).
: "Correlation between tuberous sclerosis complex 2 and glycogen synthase kinase 3 beta levels, and outcomes of patients with hepatocellular carcinoma treated by hepatectomy." in: Hepatology research : the official journal of the Japan Society of Hepatology, Vol. 44, Issue 11, pp. 1142-50, (2014) (PubMed).
: "Herbal formula Astragali Radix and Rehmanniae Radix exerted wound healing effect on human skin fibroblast cell line Hs27 via the activation of transformation growth factor (TGF-β) pathway and ..." in: Phytomedicine : international journal of phytotherapy and phytopharmacology, Vol. 20, Issue 1, pp. 9-16, (2013) (PubMed).
: "Lewis y regulate cell cycle related factors in ovarian carcinoma cell RMG-I in vitro via ERK and Akt signaling pathways." in: International journal of molecular sciences, Vol. 13, Issue 1, pp. 828-39, (2012) (PubMed).
: "Tracing putative trafficking of the glycolytic enzyme enolase via SNARE-driven unconventional secretion." in: Eukaryotic cell, Vol. 11, Issue 8, pp. 1075-82, (2012) (PubMed).
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- Cyclin D1 (CCND1)
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别名
- Cyclin D1
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背景
- Considerable effort directed towards the identification of G1 cyclins has led to the isolation of cyclin D, cyclin C and cyclin E. Of these, cyclin D corresponds to a putative human oncogene, designated PRAD1, which maps at the site of the Bcl1 rearrangement in certain lymphomas and leukemias. Two additional human type D cyclins, as well as their mouse homologs, have been identified. Evidence has established that members of the cyclin D family function to regulate phosphorylation of the retinoblastoma gene product, thereby activating E2F transcription factors.Synonyms: BCL-1 oncogene, BCL1, CCND1, Cyclin-D1, G1/S-specific cyclin-D1, PRAD-1 oncogene, PRAD1
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分子量
- approx. 36 kDa
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基因ID
- 595
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NCBI登录号
- NP_444284
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UniProt
- P24385
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途径
- PI3K-Akt Signaling, Cell Division Cycle, Mitotic G1-G1/S Phases, ER-Nucleus Signaling
抗原
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