Laminin beta 1 抗体
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Quick Overview for Laminin beta 1 抗体 (ABIN498385)
抗原
See all Laminin beta 1 (LAMB1) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of Laminin beta-1 protein. (region surrounding Asp1742)
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交叉反应 （详细）
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Species reactivity (expected):Mouse.
Species reactivity (tested):Human. -
纯化方法
- Affinity Chromatography using epitope-specific immunogen
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anti-Laminin, beta 1 (LAMB1) antibody
LAMB1 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Laminin, beta 1 (LAMB1) (AA 1053-1258) antibodyLAMB1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Laminin, beta 1 (LAMB1) antibodyKD Validated LAMB1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB1590 unconjugated Recombinant Antibody
anti-Laminin, beta 1 (LAMB1) (C-Term) antibodyLAMB1 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Laminin, beta 1 (LAMB1) (C-Term) antibodyLAMB1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Laminin, beta 1 (LAMB1) (C-Term) antibodyLAMB1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Laminin, beta 1 (LAMB1) (AA 31-270) antibodyLAMB1 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal 2D9G5 unconjugated
anti-Laminin, beta 1 (LAMB1) (AA 1-1786) antibodyLAMB1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Laminin, beta 1 (LAMB1) (AA 1691-1720), (C-Term) antibodyLAMB1 适用: 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB33607 unconjugated
anti-Laminin, beta 1 (LAMB1) (AA 1721-1770) antibodyLAMB1 适用: 人, 小鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200. Immunofluorescence: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, pH ~7.2, 0.05 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Laminin beta 1 (LAMB1) (Laminin, beta 1 (LAMB1))
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别名
- Laminin beta-1 / LAMB1
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背景
- Laminins are essential and abundant structural non-collagenous glycoproteins localizing to basement membranes. Basement membranes (cell-associated extracellular matrices (ECMs)) are polymers of Laminins with stabilizing type IV collagen networks, nidogen and several proteoglycans. Basement membranes are found under epithelial layers, around the endothelium of blood vessels and surrounding muscle, peripheral nerve and fat cells. Formation of basement membranes influences cell proliferation, phenotype, migration, gene expression and tissue architecture. Each Laminin is a heterotrimer of alpha, beta and gamma chain subunits that undergoes cell-secretion and incorporation into the ECM. Laminins can self-assemble and bind to other matrix macromolecules, and have unique and shared cell interactions mediated by Integrins, dystroglycan and cognate Laminin receptors. The human Laminin gamma-1 gene maps to chromosome 1q31 and is ubiquitously expressed in tissues that produce basement membranes.Synonyms: Laminin B1 chain, Laminin-1 subunit beta, Laminin-10 subunit beta, Laminin-12 subunit beta, Laminin-2 subunit beta, Laminin-6 subunit beta, Laminin-8 subunit beta
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分子量
- approx. 220 kDa
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基因ID
- 3912
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NCBI登录号
- NP_002282
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UniProt
- P07942
抗原
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