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Serotonin Receptor 4 抗体

HTR4 适用: 人, 大鼠, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN498370
发货至: 中国
  • 抗原 See all Serotonin Receptor 4 (HTR4) 抗体
    Serotonin Receptor 4 (HTR4)
    适用
    • 62
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    • 4
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    人, 大鼠, 小鼠
    宿主
    • 76
    • 1
    克隆类型
    • 76
    • 1
    多克隆
    标记
    • 30
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    This Serotonin Receptor 4 antibody is un-conjugated
    应用范围
    • 61
    • 27
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    • 13
    • 9
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    • 1
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    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody detects endogenous levels of SR-4 protein. (region surrounding Asp47)
    交叉反应 (详细)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    纯化方法
    Affinity Chromatography using epitope-specific immunogen
    Top Product
    Discover our top product HTR4 Primary Antibody
  • 应用备注
    Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200. Immunofluorescence: 1/50 - 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.2., 15 mM Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    Serotonin Receptor 4 (HTR4)
    别名
    Serotonin Receptor 4 / HTR4 (HTR4 产品)
    别名
    5-HT4 antibody, 5-HT<4L> antibody, 5HTR4 antibody, 5-HT4S antibody, 5-HT4R antibody, 5 hydroxytryptamine (serotonin) receptor 4 antibody, 5-hydroxytryptamine receptor 4 antibody, Htr4 antibody, HTR4 antibody
    背景
    Serotonin (also designated 5-hydroxytryptamine or 5-HT) is a molecule that functions as a neurotransmitter, a hormone and a mitogen, and it is predominantly expressed in the gut, platelets and central nervous system (CNS). In the CNS, serotonin modulates several processes, including anxiety, sleep, appetite, behavior and drug abuse. In platelets and gut, serotonin plays a major role in cardiovascular function and motility of the gastrointestinal tract, respectively. Serotonin mediates its effects through several of G protein coupled receptors, designated 5-HT receptors or alternatively SR receptors. SR-3 is a ligand-gated ion channel, whereas all other known serotonin receptor subtypes are G protein-coupled receptors. The gene which encodes SR-3 maps to human chromosome 11q23.1-q23.2. SR-4 mediates widespread effects in central and peripheral nervous systems. The gene which encodes SR-4 maps to human chromosome 5q31-q33. SR-7 belongs to the superfamily of G protein-coupled receptors. The gene which encodes SR-7 maps to human chromosome 10q21-q24.Synonyms: 5-HT-4, 5-HT4, 5-hydroxytryptamine receptor 4
    分子量
    approx. 48 kDa
    基因ID
    3360
    NCBI登录号
    NP_000861
    UniProt
    Q13639
    途径
    JAK/STAT Signaling, cAMP Metabolic Process, S100 Proteins
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