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Serotonin Receptor 3A 抗体

The 兔 多克隆 anti-Serotonin Receptor 3A antibody (ABIN498369) specifically detects Serotonin Receptor 3A in WB 和 IF. The antibody is reactive with 人 samples.
产品编号 ABIN498369
发货至: 中国
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Quick Overview for Serotonin Receptor 3A 抗体 (ABIN498369)

抗原

See all Serotonin Receptor 3A (HTR3A) 抗体
Serotonin Receptor 3A (HTR3A)

适用

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宿主

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克隆类型

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多克隆

标记

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This Serotonin Receptor 3A antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF)
  • 特异性

    This antibody detects endogenous levels of SR-3A protein. (region surrounding Trp190)

    交叉反应 (详细)

    Species reactivity (tested):Human.

    纯化方法

    Affinity chromatography

    纯度

    > 95 % by SDS-PAGE
  • 应用备注

    Western Blot: 1/500 - 1/1000. Immunofluorescence: 1/50 - 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1,0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    Serotonin Receptor 3A (HTR3A)

    背景

    Serotonin (also designated 5-hydroxytryptamine or 5-HT) is a molecule that functions as a neurotransmitter, a hormone and a mitogen, and it is predominantly expressed in the gut, platelets and central nervous system (CNS). In the CNS, serotonin modulates several processes, including anxiety, sleep, appetite, behavior and drug abuse. In platelets and gut, serotonin plays a major role in cardiovascular function and motility of the gastrointestinal tract, respectively. Serotonin mediates its effects through several of G protein coupled receptors, designated 5-HT receptors or alternatively SR receptors. SR-3 is a ligand-gated ion channel, whereas all other known serotonin receptor subtypes are G protein-coupled receptors. SR-4 mediates widespread effects in central and peripheral nervous systems. SR-7 belongs to the superfamily of G protein-coupled receptors.Synonyms: 5-HT3A, 5-HT3R, 5-hydroxytryptamine receptor 3A, Serotonin-gated ion channel receptor

    分子量

    approx. 55 kDa

    基因ID

    3359

    NCBI登录号

    NP_000860

    UniProt

    P46098

    途径

    Synaptic Membrane
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