FOXC1 抗体
Our Local Distributor
北京 101111
Quick Overview for FOXC1 抗体 (ABIN498333)
抗原
See all FOXC1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
特异性
- This antibody detects endogenous levels of FoxC1/2 protein.
-
交叉反应 （详细）
-
Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.
Also reacts to: FOXC2 -
纯化方法
- Affinity Chromatography using epitope-specific immunogen
-
-
anti-Forkhead Box C1 (FOXC1) (C-Term) antibody
Verified FOXC1 适用: 人 ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Forkhead Box C1 (FOXC1) antibodyFOXC1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box C1 (FOXC1) (AA 1-79) antibodyFOXC1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box C1 (FOXC1) (AA 488-515), (C-Term) antibodyFOXC1 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB22897 unconjugated
anti-Forkhead Box C1 (FOXC1) (Center) antibodyFOXC1 适用: 人, 小鼠, 大鼠, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box C1 (FOXC1) (AA 101-200) antibodyFOXC1 适用: 人, 小鼠, 大鼠, 山羊 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box C1 (FOXC1) (AA 62-186) antibodyFOXC1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box C1 (FOXC1) (Internal Region) antibodyVerified FOXC1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Forkhead Box C1 (FOXC1) (AA 406-455) antibodyFOXC1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box C1 (FOXC1) (AA 464-553) antibodyFOXC1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4D11 unconjugated
-
-
应用备注
-
Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 50 - 1: 200. Immunoflourescence: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
浓度
- 1.0 mg/mL
-
缓冲液
- Phosphate buffered saline (PBS), pH 7.2, 0.05 % Sodium Azide
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
-
- FOXC1 (Forkhead Box C1 (FOXC1))
-
别名
- FOXC1 / FKHL7 / FREAC3
-
背景
- FOXC2 is a member of forkhead/winged helix transcription factor family whose members serve as key regulators in embryogenesis and cell differentiation. FOXC2 functions as a key regulator of adipocyte metabolism by increasing the sensitivity of the β-adrenergic-cAMP-protein kinase A (PKA) signaling pathway through alteration of adipocyte PKA holoenzyme composition. Increased FOXC2 levels, induced by high fat diet, seem to counteract most of the symptoms associated with obesity. FOXC2 expression is also associated with the early stage of chondrogenic differentiation both in vivo and in vitro. FOXC2 haploinsufficiency results in Lymphedema-distichiasis (LD), an autosomal dominant disorder that classically presents as lymphedema of the limbs and double rows of eyelashes (distichiasis). Mutant mice null for FOXC2 show defects in axial and cranial skeletogenesis, suggesting a requirement of FOXC2 for skeletal tissue development.Synonyms: FREAC-3, Forkhead box protein C1, Forkhead-related protein FKHL7, Forkhead-related transcription factor 3
-
分子量
- approx. 57 kDa
-
基因ID
- 2296
-
NCBI登录号
- NP_001444
-
UniProt
- Q12948
-
途径
- Chromatin Binding, Glycosaminoglycan Metabolic Process
抗原
-
