SKIL 抗体
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北京 101111
Quick Overview for SKIL 抗体 (ABIN498307)
抗原
See all SKIL 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of SnoN protein. (region surrounding Asp652)
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交叉反应 (详细)
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Species reactivity (expected):Mouse.
Species reactivity (tested):Human. -
纯化方法
- Affinity chromatography using epitope-specific immunogen
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纯度
- > 95 % (by SDS-PAGE)
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应用备注
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Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 500 - 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- SKIL (SKI-Like Oncogene (SKIL))
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别名
- SKIL / SnoN
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背景
- SnoN may have a regulatory role in cell division or differentiation in response to extracellular signals. SnoN acts as a positive mediator of TGF beta induced transcription and cell cycle arrest in lung epithelial cells. The ability of SnoN to repress the growth inhibitory function of the Smad proteins is required for their transforming activity.Synonyms: SNO, Ski-like protein, Ski-related novel protein N, Ski-related oncogene, Ski-related protein, SnoA, Snol
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分子量
- approx. 77 kDa
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基因ID
- 6498
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NCBI登录号
- NP_001138569
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UniProt
- P12757
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途径
- Positive Regulation of Response to DNA Damage Stimulus
抗原
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