KAT5 抗体
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北京 101111
Quick Overview for KAT5 抗体 (ABIN498216)
抗原
See all KAT5 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of TIP60 protein.
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交叉反应 （详细）
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Species reactivity (expected):Mouse.
Species reactivity (tested):Human. -
纯化方法
- Affinity chromatography using epitope-specific immunogen
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纯度
- > 95 % (by SDS-PAGE)
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anti-K(lysine) Acetyltransferase 5 (KAT5) (AA 18-208) antibody
KAT5 适用: 人 ELISA, WB, FACS 宿主: 小鼠 Monoclonal 2A11H7 unconjugated
anti-K(lysine) Acetyltransferase 5 (KAT5) (AA 3-512) antibodyKAT5 适用: 人 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-K(lysine) Acetyltransferase 5 (KAT5) (AA 1-513) antibodyKAT5 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-K(lysine) Acetyltransferase 5 (KAT5) (AA 18-208) antibodyKAT5 适用: 人 ELISA 宿主: 小鼠 Monoclonal 4B3B4 unconjugated
anti-K(lysine) Acetyltransferase 5 (KAT5) antibodyKAT5 适用: 人 ELISA, IHC 宿主: 小鼠 Monoclonal 3F9 unconjugated
anti-K(lysine) Acetyltransferase 5 (KAT5) (AA 33-64), (N-Term) antibodyKAT5 适用: 人 WB 宿主: 兔 Polyclonal RB05776 unconjugated
anti-K(lysine) Acetyltransferase 5 (KAT5) (C-Term) antibodyKAT5 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, 山羊, 豚鼠, 马, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-K(lysine) Acetyltransferase 5 (KAT5) (pSer86) antibodyKAT5 适用: 小鼠, 大鼠 ELISA, WB, IHC (p), IF (cc), IF (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-K(lysine) Acetyltransferase 5 (KAT5) antibodyKAT5 适用: 人 ICC, DB 宿主: 小鼠 Monoclonal 3557C4a unconjugated
anti-K(lysine) Acetyltransferase 5 (KAT5) (AA 480-530) antibodyKAT5 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry on paraffin sections: 1: 50 - 1: 200. Immunoflourescence: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- KAT5 (K(lysine) Acetyltransferase 5 (KAT5))
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别名
- KAT5
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背景
- MOZ (monocytic leukemia zinc-finger protein) is a chromatin-associated histone acetyltransferase (HAT) that regulates chromatin remodeling and transcription. The MOZ gene was initially isolated as a consequence of two variant translocations that were identified in a distinct subtype of acute myeloid leukemias and resulted in the formation of MOZ fusion proteins. These fusions involve the HAT domain of MOZ with the activation domain of either transcriptional co-activator protein TIF2/GRIP1 or CBP, and lead to enhanced transcriptional activation by a mechanism involving aberrant histone acetylation. Additional MOZ-related proteins, including MORF (MOZrelated factor) and TIP60 (TAT-interacting proteins 60), share significant similarities with MOZ including the putuative HAT domain. MORF also contains a strong transcriptional repression domain at its N-terminus and a highly potent activation domain at the C-terminus, suggesting that MORF has both HAT activity and contributes to the regulation of transcriptional activation. TIP60 was originally identified as a co-activator for the HIV TAT protein and also functions as a nuclear hormone receptor co-activator that enhances ligand dependent steroid receptor-mediated transactivation involving the androgen, estrogen and progesterone receptors.Synonyms: 60 kDa Tat-interactive protein, HIV-1 Tat interactive protein, HTATIP, Histone acetyltransferase HTATIP, Histone acetyltransferase KAT5, Lysine acetyltransferase 5, PLIP, TIP60, cPLA(2)-interacting protein
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基因ID
- 10524
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NCBI登录号
- NP_006379
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UniProt
- Q92993
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway
抗原
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